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Table 3 Lysophosphatidylcholine and oxysterols in carotid plaques from control and type 2 diabetic patients. Data are expressed as mean +/- S.D. (for normal distribution), medians [25th-75th percentiles]. Groups were compared with a Student’s test or Kruskall-Wallis non-parametric test

From: Inflammation and oxidative stress markers in type 2 diabetes patients with Advanced Carotid atherosclerosis

 

Controls

Type 2 Diabetics

p.overall

 

N = 98

 N = 101

 

Total LPC

(mmol/mol cholesterol)

5.23 [3.05;6.93]

4.84 [3.36;8.10]

0.941

 

LPC relative levels

  

16.0.LPC.sn1

40.5 (2.81)

40.8 (3.10)

0.543

16.0.LPC.sn2

6.84 [6.07;7.46]

6.82 [6.12;7.55]

0.977

18.2.LPC.sn1

5.38 [4.08;6.84]

5.26 [3.89;6.89]

0.829

18.2.LPC.sn2

1.06 [0.74;1.37]

1.02 [0.80;1.44]

0.946

18.1.LPC.sn1

10.0 (2.04)

9.83 (1.81)

0.505

18.1.LPC.sn2

1.83 [1.54;2.23]

1.88 [1.52;2.12]

0.870

18.0.LPC.sn1

26.2 (4.18)

25.5 (4.28)

0.294

18.0.LPC.sn2

4.52 [3.92;5.44]

4.49 [3.65;5.29]

0.333

20.4.LPC.sn1

1.50 [1.13;1.98]

1.55 [1.19;2.26]

0.132

20.4.LPC.sn2

0.37 [0.26;0.62]

0.45 [0.34;0.75]

0.013

20.3.LPC.sn1

0.84 [0.65;1.07]

0.87 [0.68;1.21]

0.201

20.3.LPC.sn2

0.20 [0.14;0.26]

0.19 [0.15;0.30]

0.337

Oxysterols (mmol/mol cholesterol)

27-Hydroxycholesterol

3.33 [2.02;7.25]

3.35 [1.84;6.74]

0.945

25-Hydroxycholesterol

0.39 [0.28;0.62]

0.43 [0.30;0.75]

0.273

7α-Hydroxycholesterol

0.75 [0.44;1.11]

0.78 [0.49;1.47]

0.246

7β-Hydroxycholesterol

0.94 [0.64;1.27]

1.11 [0.70;1.76]

0.063

7-ketocholesterol

2.03 [1.16;3.88]

1.93 [1.11;3.94]

0.940