Table 2 Plasma oxysterols levels and inflammation biomarkers in controls and diabetic patients. Data are expressed as medians [25th-75th percentiles]. Groups were compared with a Mann- Whitney non-parametric test
Controls | Type 2 diabetics | p.overall | |
|---|---|---|---|
Oxysterols (mmol/mol cholesterol) | |||
7α-Hydroxycholesterol | 0.31 [0.21;0.42] | 0.36 [0.26;0.46] | 0.029 |
7β-Hydroxycholesterol | 0.39 [0.26;0.52] | 0.47 [0.33;0.66] | 0.040 |
7-ketocholesterol | 0.85 [0.59;1.37] | 0.90 [0.70;1.38] | 0.166 |
25-hydroxycholesterol | 0.14 [0.11;0.19] | 0.14 [0.10;0.22] | 0.854 |
27-hydroxycholesterol | 0.04 [0.03;0.05] | 0.04 [0.03;0.06] | 0.652 |
Hs CRP (mg/L). | 1.85 [0.96;4.75] | 3.24 [1.17;8.75] | 0.028 |
IL-1β (ng/l) | 0.05 [0.05;0.08] | 0.06 [0.05;0.12] | 0.017 |
IL-18 (µg/l) | 0.61 [0.45;0.85] | 0.70 [0.50;0.96] | 0.098 |
IL-6 (ng/l) | 5.14 [4.02;10.1] | 4.97 [3.73;7.43] | 0.273 |