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  1. It is unknown whether high hemoglobin A1c (HbA1c) is associated with increases in the risk of cardiovascular disease among individuals with elevated genetic susceptibility. We aimed to investigate the associat...

    Authors: Juntae Kim, Dongmin Kim, Han-Joon Bae, Byoung-Eun Park, Tae Soo Kang, Seong-Hoon Lim, Su Yeon Lee, Young Hak Chung, Ji Wung Ryu, Myung-Yong Lee, Pil-Sung Yang and Boyoung Joung
    Citation: Cardiovascular Diabetology 2024 23:5
  2. Numerous clinical studies have explored sodium–glucose cotransporter 2 inhibitor (SGLT2i) in patients with chronic heart failure (CHF), with or without type 2 diabetes mellitus (T2DM), and SGLT2i were proved t...

    Authors: Jiao Chen, Chunxia Jiang, Man Guo, Yan Zeng, Zongzhe Jiang, Dongmin Zhang, Mengqin Tu, Xiaozhen Tan, Pijun Yan, XunMei Xu, Yang Long and Yong Xu
    Citation: Cardiovascular Diabetology 2024 23:2
  3. Obesity has increased in recent years with consequences on diabetes and other comorbidities. Thus, 1 out of 3 diabetic patients suffers cardiovascular disease (CVD). The network among glucose, immune system, e...

    Authors: David García-Vega, David Sánchez-López, Gemma Rodríguez-Carnero, Rocío Villar-Taibo, Juan E. Viñuela, Adán Lestegás-Soto, Ana Seoane-Blanco, María Moure-González, Susana B. Bravo, Ángel L. Fernández, José R. González-Juanatey and Sonia Eiras
    Citation: Cardiovascular Diabetology 2024 23:1
  4. This study aimed to investigate the risks of all-cause and cardiovascular mortality associated with blood pressure (BP) levels of 130–139/80–89 mmHg in Chinese adults with different glucose metabolism, during ...

    Authors: Chang-Sheng Sheng, Haiyan Wang, Yanjun Liu, Yanyun Li, TianZhiChao Hou, Miaoyan Qiu, Yao Lu, Siming Sun, Junhan Yang, Xiaomin Song, Guang Ning and Jingyan Tian
    Citation: Cardiovascular Diabetology 2023 22:353
  5. Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease...

    Authors: Jinbo Hu, Qinglian Zeng, Xiangjun Chen, Wenjin Luo, Ziwei Tang, Mei Mei, Wenrui Zhao, Zhipeng Du, Zhiping Liu, Qifu Li, Qingfeng Cheng and Shumin Yang
    Citation: Cardiovascular Diabetology 2023 22:352
  6. Adiposity and elevated inflammation are two hallmarks of hyperglycemia. However, it is unknown whether clustering of elevated inflammation and adiposity interact act on diabetogenesis and lead to a greater ris...

    Authors: Dan Wu, Yulong Lan, Shuohua Chen, Xiong Ding, Guanzhi Chen, Chutao Wu, Lois Balmer, Wencan Xu, Shouling Wu and Wei Wang
    Citation: Cardiovascular Diabetology 2023 22:351
  7. Elevated glycated hemoglobin (HbA1c) is associated with a higher burden of subclinical atherosclerosis (SA). However, the association with SA of earlier insulin resistance markers is poorly understood. The stu...

    Authors: Josep Iglesies-Grau, Ana Garcia-Alvarez, Belén Oliva, Guiomar Mendieta, Inés García-Lunar, José J. Fuster, Ana Devesa, Cristina Pérez-Herreras, Antonio Fernández-Ortiz, Ramon Brugada, Borja Ibanez, Rodrigo Fernandez-Jimenez and Valentin Fuster
    Citation: Cardiovascular Diabetology 2023 22:350
  8. We recently demonstrated that treatment with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) leads to an increase in myocardial flow reserve in patients with type 2 diabetes (T2D) with stable coronary arte...

    Authors: Francesca Cinti, Lucia Leccisotti, Gian Pio Sorice, Umberto Capece, Domenico D’Amario, Margherita Lorusso, Shawn Gugliandolo, Cassandra Morciano, Andrea Guarneri, Maria Angela Guzzardi, Teresa Mezza, Amedeo Capotosti, Luca Indovina, Pietro Manuel Ferraro, Patricia Iozzo, Filippo Crea…
    Citation: Cardiovascular Diabetology 2023 22:349
  9. Prediabetes, an intermediate stage between normal blood sugar levels and a diabetes mellitus diagnosis, is increasing in prevalence. Severe prediabetes is associated with a similar risk of complications as dia...

    Authors: Jung-Chi Hsu, Yen-Yun Yang, Shu-Lin Chuang, Jen-Kuang Lee and Lian-Yu Lin
    Citation: Cardiovascular Diabetology 2023 22:348
  10. Previous studies have found that the triglyceride glucose index (TyG index) trajectories are associated with cardiovascular diseases. However, the association between the patterns of TyG index trajectories and...

    Authors: Fengling Xin, Shuyou He, Yu Zhou, Xueni Jia, Yulong Zhao and Hui Zhao
    Citation: Cardiovascular Diabetology 2023 22:347
  11. This study aimed to evaluate the association of triglyceride-glucose (TyG) index, an insulin resistance surrogate biomarker, with first stroke in a hypertensive population and to explore potential influencing ...

    Authors: Nan Zhang, Xiying Chi, Ziyi Zhou, Yun Song, Shuqun Li, Jiafeng Xu and Jianping Li
    Citation: Cardiovascular Diabetology 2023 22:346
  12. The association between obesity indicators and mortality in individuals with diabetes remains unclear, and data on cardiovascular mortality are scarce. Therefore, we investigated the associations between the f...

    Authors: Chung-Yen Lu, Hsiao-Hui Chen, Kuan-Hui Chi and Pei-Chun Chen
    Citation: Cardiovascular Diabetology 2023 22:345
  13. In the last years, the classical pattern of diabetic kidney disease (DKD) has been partially overcome, because of the uncovering of a new DKD phenotype with significant renal dysfunction without presence of al...

    Authors: Maurizio Di Marco, Sabrina Scilletta, Nicoletta Miano, Nicola Marrano, Annalisa Natalicchio, Francesco Giorgino, Stefania Di Mauro, Agnese Filippello, Alessandra Scamporrino, Paola Tribulato, Giosiana Bosco, Francesco Di Giacomo Barbagallo, Roberto Scicali, Agostino Milluzzo, Teresa Ballirò, Lucia Frittitta…
    Citation: Cardiovascular Diabetology 2023 22:344
  14. Prior studies suggest a link between metabolic dysfunction-associated steatotic liver disease (MASLD) and incident arrhythmias, including atrial fibrillation (AF). However, robust data are lacking from cohorts...

    Authors: Tracey G. Simon, Fahim Ebrahimi, Bjorn Roelstraete, Hannes Hagström, Johan Sundström and Jonas F. Ludvigsson
    Citation: Cardiovascular Diabetology 2023 22:343
  15. Data are limited on the association of metabolic dysfunction-associated fatty liver disease (MAFLD) with systemic atherosclerosis. This study aimed to examine the relationship between MAFLD and the extent of a...

    Authors: Yanli Zhang, Zhang Xia, Xueli Cai, Xin Su, Aoming Jin, Lerong Mei, Jing Jing, Suying Wang, Xia Meng, Shan Li, Mengxing Wang, Tiemin Wei, Yongjun Wang, Yan He and Yuesong Pan
    Citation: Cardiovascular Diabetology 2023 22:342
  16. Previous studies using trajectory models focused on examining the longitudinal changes in triglyceride-glucose (TyG) levels and lifestyle scores separately, without exploring the joint evolution of these two f...

    Authors: Hui Zhou, Xiong Ding, Yulong Lan, Shuohua Chen, Shouling Wu and Dan Wu
    Citation: Cardiovascular Diabetology 2023 22:341
  17. Olive oil consumption has been inversely associated with the risk of type 2 diabetes (T2D) and cardiovascular disease (CVD). However, the impact of olive oil consumption on plasma metabolites remains poorly un...

    Authors: Jesús F. García-Gavilán, Nancy Babio, Estefanía Toledo, Zhila Semnani-Azad, Cristina Razquin, Courtney Dennis, Amy Deik, Dolores Corella, Ramón Estruch, Emilio Ros, Montserrat Fitó, Fernando Arós, Miquel Fiol, José Lapetra, Rosa Lamuela-Raventos, Clary Clish…
    Citation: Cardiovascular Diabetology 2023 22:340
  18. The risk of cardiovascular disease (CVD) depended on the magnitude and exposure duration of insulin resistance (IR). This study aimed to investigate the associations of cumulative metabolic score for IR (cumME...

    Authors: Xue Tian, Shuohua Chen, Qin Xu, Xue Xia, Yijun Zhang, Penglian Wang, Shouling Wu and Anxin Wang
    Citation: Cardiovascular Diabetology 2023 22:339
  19. Previous observational studies have documented an inverse association of birthweight with myocardial infarction (MI) but a positive association with atrial fibrillation (AF). However, the causality of these as...

    Authors: Lijie Kong, Yiying Wang, Chaojie Ye, Chun Dou, Dong Liu, Min Xu, Jie Zheng, Ruizhi Zheng, Yu Xu, Mian Li, Zhiyun Zhao, Jieli Lu, Yuhong Chen, Weiqing Wang, Ruixin Liu, Yufang Bi…
    Citation: Cardiovascular Diabetology 2023 22:338
  20. Subjects with type 2 diabetes (T2D) have a higher risk of in-stent restenosis and stent thrombosis. The activation of the glucagon-like peptide-1 receptor (GLP-1R) has been suggested to induce several effects ...

    Authors: Irene Santos-Pardo, Nils Witt, Oskar Angerås and Thomas Nyström
    Citation: Cardiovascular Diabetology 2023 22:337
  21. The effects of diabetes on the cardiac and aortic structure and function remain unclear. Detecting and intervening these variations early is crucial for the prevention and management of complications. Cardiova...

    Authors: Zhaoyue Li, Jie Xiong, Yutong Guo, Hao Tang, Bingchen Guo, Bo Wang, Dianyu Gao, Zengxiang Dong and Yingfeng Tu
    Citation: Cardiovascular Diabetology 2023 22:336
  22. The assessment of obesity-related health risks has traditionally relied on the Body Mass Index and waist circumference, but their limitations have propelled the need for a more comprehensive approach. The diff...

    Authors: Marta Lopez-Yus, Carmen Casamayor, Juan Jose Soriano-Godes, Sofia Borlan, Yolanda Gonzalez-Irazabal, Maria Pilar Garcia-Sobreviela, Beatriz Garcia-Rodriguez, Raquel del Moral-Bergos, Pilar Calmarza, Jose Maria Artigas, Silvia Lorente-Cebrian, Vanesa Bernal-Monterde, Alejandro Sanz-Paris and Jose M. Arbones-Mainar
    Citation: Cardiovascular Diabetology 2023 22:335
  23. Stress hyperglycemia ratio (SHR), associated with adverse outcomes in patients with ST-segment elevation myocardial infarction (STEMI), has several definitions. This study aims to assess the prognostic value o...

    Authors: Wang Liao, Yuwen Chen, Qiyue Gao, Rongrong Gan, Ming Li, Zhenliang Liu, Jiasheng Liang, Henghua Cui, Kaida Ren, Yabin Liu, Zhengdong Wang, Jun Jiang and Qucheng Wei
    Citation: Cardiovascular Diabetology 2023 22:334
  24. Insulin resistance is a pivotal risk factor for cardiovascular diseases, and the triglyceride-glucose (TyG) index is a well-established surrogate of insulin resistance. This study aimed to investigate the prog...

    Authors: Yu Zhang, Ce Zhang, Lin Jiang, Lianjun Xu, Jian Tian, Xueyan Zhao, Dong Wang, Yin Zhang, Kai Sun, Channa Zhang, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Jizheng Wang, Xinxing Feng…
    Citation: Cardiovascular Diabetology 2023 22:333
  25. Concurrent insulin resistance and elevated blood pressure are commonly observed in cardiovascular disease (CVD) and have long been proposed to contribute to CVD. However, the temporal relationship between them...

    Authors: Kuangyi Wu, Huancong Zheng, Weiqiang Wu, Guanzhi Chen, Zefeng Cai, Zhiwei Cai, Yulong Lan, Dan Wu, Shouling Wu and Youren Chen
    Citation: Cardiovascular Diabetology 2023 22:332
  26. Endothelial–mesenchymal transition (EndMT) plays a crucial role in promoting myocardial fibrosis and exacerbating cardiac dysfunction. Dapagliflozin (DAPA) is a sodium–glucose-linked transporter 2 (SGLT-2) inh...

    Authors: Weijie Wang, Yilan Li, Yanxiu Zhang, Tao Ye, Kui Wang, Shuijie Li and Yao Zhang
    Citation: Cardiovascular Diabetology 2023 22:331
  27. This post-hoc analysis of the DELIGHT trial assessed effects of the SGLT2 inhibitor dapagliflozin on iron metabolism and markers of inflammation.

    Authors: Akihiko Koshino, Brendon L. Neuen, Niels Jongs, Carol Pollock, Peter J. Greasley, Eva-Marie Andersson, Ann Hammarstedt, Cecilia Karlsson, Anna Maria Langkilde, Takashi Wada and Hiddo J.L. Heerspink
    Citation: Cardiovascular Diabetology 2023 22:330
  28. Authors: Kamel Mohammedi, Audrey Cordon, Vincent Rigalleau, Ninon Foussard, Céline Bairras-Martin, Thierry Couffinhal, Julien Bezin and Antoine Benard
    Citation: Cardiovascular Diabetology 2023 22:329
  29. In the Netherlands, more than one million patients have type 2 diabetes (T2D), and approximately 36% of these patients have chronic kidney disease (CKD). Yearly medical costs related to T2D and CKD account for...

    Authors: Sara W. Quist, Alexander V. van Schoonhoven, Stephan J. L. Bakker, Michał Pochopień, Maarten J. Postma, Jeanni M. T. van Loon and Jeroen H. J. Paulissen
    Citation: Cardiovascular Diabetology 2023 22:328
  30. Matrix metalloproteinase 12 (MMP12) is a macrophage-secreted protein that is massively upregulated as a pro-inflammatory factor in metabolic and vascular tissues of mice and humans suffering from cardiometabol...

    Authors: Melina Amor, Valentina Bianco, Martin Buerger, Margarete Lechleitner, Nemanja Vujić, Anja Dobrijević, Alena Akhmetshina, Anita Pirchheim, Birgit Schwarz, Ariane R. Pessentheiner, Franziska Baumgartner, Katharina Rampitsch, Silvia Schauer, Iva Klobučar, Vesna Degoricija, Gudrun Pregartner…
    Citation: Cardiovascular Diabetology 2023 22:327
  31. Advanced glycation end products (AGEs) have been linked to cardiovascular disease (CVD), especially coronary heart disease (CHD), but their role in CVD pathogenesis remains unclear. Therefore, we investigated ...

    Authors: Jinluan Chen, Banafsheh Arshi, Komal Waqas, Tianqi Lu, Daniel Bos, M. Arfan Ikram, André G. Uitterlinden, Maryam Kavousi and M. Carola Zillikens
    Citation: Cardiovascular Diabetology 2023 22:326
  32. The triglyceride-glucose (TyG) index is a predictor of cardiovascular diseases; however, to what extent the TyG index is associated with cardiovascular diseases through renal function is unclear. This study ai...

    Authors: Cancan Cui, Lin Liu, Te zhang, Ling Fang, Zhanhao Mo, Yitian Qi, Jia Zheng, Zhijia Wang, Haikun Xu, Han Yan, Siqi Yue, Xuekui Wang and Zhiyuan Wu
    Citation: Cardiovascular Diabetology 2023 22:325
  33. Bempedoic Acid (BA) is a novel Lipid-Lowering Therapy (LLT). We performed a systematic review and meta-analysis to assess the efficacy and safety of BA in patients with hypercholesterolemia.

    Authors: Ovidio De Filippo, Fabrizio D’Ascenzo, Mario Iannaccone, Maurizio Bertaina, Attilio Leone, Irene Borzillo, Emanuele Ravetti, Andrea Solano, Ilaria Pagliassotto, Marco Nebiolo, Francesco Bruno, Federico Giacobbe, Saverio Muscoli, Silvia Monticone, Maria Felice Brizzi, Giuseppe Biondi Zoccai…
    Citation: Cardiovascular Diabetology 2023 22:324
  34. An obesity paradox has been described in relation to adverse clinical outcomes (e.g., mortality) with lower body mass index (BMI).

    Authors: Tadeusz Osadnik, Dariusz Nowak, Kamila Osadnik, Marek Gierlotka, Adam Windak, Tomasz Tomasik, Mirosław Mastej, Beata Łabuz-Roszak, Kacper Jóźwiak, Gregory Y. H. Lip, Dimitri P. Mikhailidis, Peter P. Toth, Naveed Sattar, Marcin Goławski, Jacek Jóźwiak and Maciej Banach
    Citation: Cardiovascular Diabetology 2023 22:323
  35. The triglyceride-glucose (TyG) index has been proposed as a reliable surrogate marker of insulin resistance and an independent predictor of major adverse cardiovascular events (MACEs). Several recent studies h...

    Authors: Shiyi Tao, Lintong Yu, Jun Li, Zicong Xie, Li Huang, Deshuang Yang, Yuqing Tan, Wenjie Zhang, Xuanchun Huang and Tiantian Xue
    Citation: Cardiovascular Diabetology 2023 22:322
  36. This study aimed to investigate the association between the triglyceride–glucose (TyG) index and left ventricular global longitudinal strain (GLS) in patients with coronary heart disease and to examine the rol...

    Authors: Lin Na, Wenjing Cui, Xinqi Li, Jing Chang and Xin Xue
    Citation: Cardiovascular Diabetology 2023 22:321
  37. The Triglyceride-glucose (TyG) index, a novel indicator of insulin resistance, has been associated with mortality from coronary artery diseases, ischemic stroke, and heart failure. In recent years, much emphas...

    Authors: Jiaqi Chen, Kangxiang Wu, Yiying Lin, Mingyuan Huang and Shanghe Xie
    Citation: Cardiovascular Diabetology 2023 22:320
  38. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which have proven cardiovascular benefits, are recommended in people with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD). Howeve...

    Authors: Xi Tan, Yuanjie Liang, Jigar R. Rajpura, Larisa Yedigarova, Josh Noone, Lin Xie, Silvio Inzucchi and Adam de Havenon
    Citation: Cardiovascular Diabetology 2023 22:319
  39. Diabetes mellitus (DM), heart failure (HF) and metabolic dysfunction associated steatotic liver disease (MASLD) are overlapping diseases of increasing prevalence. Because there are still high numbers of patien...

    Authors: Katarzyna Nabrdalik, Hanna Kwiendacz, Krzysztof Irlik, Mirela Hendel, Karolina Drożdż, Agata M. Wijata, Jakub Nalepa, Oliwia Janota, Wiktoria Wójcik, Janusz Gumprecht and Gregory Y. H. Lip
    Citation: Cardiovascular Diabetology 2023 22:318
  40. Diabetes mellitus (DM) is the most common metabolic disease worldwide and a major risk factor for adverse cardiovascular events, while the additive effects of DM on left ventricular (LV) deformation in the res...

    Authors: Yue Gao, Yi-Ning Jiang, Rui Shi, Ying-Kun Guo, Hua-Yan Xu, Chen-Yan Min, Zhi-Gang Yang and Yuan Li
    Citation: Cardiovascular Diabetology 2023 22:317
  41. Heart failure (HF), chronic kidney disease (CKD), and type 2 diabetes mellitus (T2DM) are common and interrelated conditions, each with a significant burden of disease. HF and kidney disease progress through p...

    Authors: Robert J. Mentz, Stephen A. Brunton and Janani Rangaswami
    Citation: Cardiovascular Diabetology 2023 22:316
  42. The association of glycemic variability with severe consciousness disturbance and in-hospital all-cause mortality in critically ill patients with cerebrovascular disease (CVD) remains unclear, This study aimed...

    Authors: Weimin Cai, Yaling Li, Kun Guo, Xiao Wu, Chao Chen and Xinran Lin
    Citation: Cardiovascular Diabetology 2023 22:315
  43. Diabetes microangiopathy, a hallmark complication of diabetes, is characterised by structural and functional abnormalities within the intricate network of microvessels beyond well-known and documented target o...

    Authors: Dídac Mauricio, Mònica Gratacòs and Josep Franch-Nadal
    Citation: Cardiovascular Diabetology 2023 22:314
  44. Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited evidence for the effect of long-term elevation of AIP on ischemic stroke. Therefore, we a...

    Authors: Huancong Zheng, Kuangyi Wu, Weiqiang Wu, Guanzhi Chen, Zekai Chen, Zefeng Cai, Zhiwei Cai, Yulong Lan, Shouling Wu and Youren Chen
    Citation: Cardiovascular Diabetology 2023 22:313
  45. Metabolic cardiomyopathy (MCM), characterized by intramyocardial lipid accumulation, drives the progression to heart failure with preserved ejection fraction (HFpEF). Although evidence suggests that the mammal...

    Authors: Sarah Costantino, Alessandro Mengozzi, Srividya Velagapudi, Shafeeq Ahmed Mohammed, Era Gorica, Alexander Akhmedov, Alessia Mongelli, Nicola Riccardo Pugliese, Stefano Masi, Agostino Virdis, Andreas Hülsmeier, Christian Matthias Matter, Thorsten Hornemann, Giovanni Melina, Frank Ruschitzka, Thomas Felix Luscher…
    Citation: Cardiovascular Diabetology 2023 22:312
  46. Prior research has established the correlation between insulin resistance (IR) and hypertension. While the association between triglyceride-glucose (TyG) index, a reliable surrogate marker of IR, and uncontrol...

    Authors: Liao Tan, Yubo Liu, Jie Liu, Guogang Zhang, Zhaoya Liu and Ruizheng Shi
    Citation: Cardiovascular Diabetology 2023 22:311
  47. There is growing evidence that ceramides play a significant role in the onset and progression of non-alcoholic fatty liver disease (NAFLD), a highly prevalent condition in patients with type 2 diabetes associa...

    Authors: Damien Denimal, Sarah Béland-Bonenfant, Jean-Paul Pais-de-Barros, Alexia Rouland, Benjamin Bouillet, Laurence Duvillard, Bruno Vergès and Jean-Michel Petit
    Citation: Cardiovascular Diabetology 2023 22:310
  48. The triglyceride glucose-body mass (TyG-BMI) index is acknowledged as both a reliable indicator of the risk of cardiovascular disease and an accurate surrogate biomarker for evaluating insulin resistance (IR)....

    Authors: Jiahao Dou, Chen Guo, Yawen Wang, Zihe Peng, Ruiyun Wu, Qiangqiang Li, Hong Zhao, Shoufang Song, Xuelu Sun and Jin Wei
    Citation: Cardiovascular Diabetology 2023 22:309
  49. Previous studies have investigated the association between the ratio of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C) and the incidence of diabetes in adults and discovered that a high TG/...

    Authors: Hiroki Yuge, Hiroshi Okada, Masahide Hamaguchi, Kazushiro Kurogi, Hiroaki Murata, Masato Ito and Michiaki Fukui
    Citation: Cardiovascular Diabetology 2023 22:308
  50. This study aimed to explore the association between the triglyceride-glucose (TyG) index and the risk of in-hospital mortality in critically ill patients with sepsis.

    Authors: Rui Zheng, Songzan Qian, Yiyi Shi, Chen Lou, Honglei Xu and Jingye Pan
    Citation: Cardiovascular Diabetology 2023 22:307

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