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  1. We aimed to identify a lipidic profile associated with type 2 diabetes mellitus (T2DM) development in coronary heart disease (CHD) patients, to provide a new, highly sensitive model which could be used in clin...

    Authors: Alejandro Villasanta-Gonzalez, Marina Mora-Ortiz, Juan F. Alcala-Diaz, Lorenzo Rivas-Garcia, Jose D. Torres-Peña, Asuncion Lopez-Bascon, Monica Calderon-Santiago, Antonio P. Arenas-Larriva, Feliciano Priego‑Capote, Maria M. Malagon, Fabian Eichelmann, Pablo Perez-Martinez, Javier Delgado-Lista, Matthias B. Schulze, Antonio Camargo and Jose Lopez-Miranda
    Citation: Cardiovascular Diabetology 2023 22:199
    Content type: Research Published on:

  2. Patients with heart failure have increased cardiac filling pressures, circulating natriuretic peptides, and physical signs of fluid retention, which are related to sodium retention by the kidneys and are allev...

    Authors: Milton Packer
    Citation: Cardiovascular Diabetology 2023 22:197
    Content type: Comment Published on:

  4. Type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease (CKD), are recognized among the most disruptive public health issues of the current century. A large body of evidence from epidemi...

    Authors: Marella Marassi and Gian Paolo Fadini
    Citation: Cardiovascular Diabetology 2023 22:195
    Content type: Review Published on:

  5. The overactivation of mineralocorticoid receptor (MR) plays a key pathological role in the progression of cardiovascular and renal diseases by promoting pro-inflammatory and pro-fibrotic signaling. Recently, i...

    Authors: Atsushi Tanaka, Hirotaka Shibata, Takumi Imai, Hisako Yoshida, Motoaki Miyazono, Naohiko Takahashi, Daiju Fukuda, Yosuke Okada, Hiroki Teragawa, Satoru Suwa, Keisuke Kida, Masao Moroi, Isao Taguchi, Shigeru Toyoda, Michio Shimabukuro, Kengo Tanabe…
    Citation: Cardiovascular Diabetology 2023 22:194
    Content type: Study Protocol Published on:

  6. We aimed to examine the association between smoking behavior change and risk of cardiovascular disease (CVD) incidence and mortality in patients with type 2 diabetes mellitus (T2DM).

    Authors: Su-Min Jeong, Jung Eun Yoo, Junhee Park, Wonyoung Jung, Kyu Na Lee, Kyungdo Han, Cheol Min Lee, Ki-Woong Nam, Seung-Pyo Lee and Dong Wook Shin
    Citation: Cardiovascular Diabetology 2023 22:193
    Content type: Research Published on:

  7. The prevalence of obesity and atrial fibrillation (AF), which are inextricably linked, is rapidly increasing worldwide. Obesity rates are higher among patients with AF than healthy individuals. Some epidemiolo...

    Authors: Hongyang Shu, Jia Cheng, Na Li, Zixuan Zhang, Jiali Nie, Yizhong Peng, Yan Wang, Dao Wen Wang and Ning Zhou
    Citation: Cardiovascular Diabetology 2023 22:192
    Content type: Review Published on:

  8. Given the cumulative evidence on the effectiveness of sodium-glucose cotransporter 2 inhibitors (SGLT2is) on chronic heart failure, demand is emerging for further information on their effects in patients who a...

    Authors: Sohee Park, Han Eol Jeong, Hyesung Lee, Seng Chan You and Ju-Young Shin
    Citation: Cardiovascular Diabetology 2023 22:191
    Content type: Research Published on:

  9. Triglyceride-glucose (TyG) index is an efficient indicator of insulin resistance and is proven to be a valuable marker in several cardiovascular diseases. However, the relationship between TyG index and cardia...

    Authors: Yang Boshen, Zhu Yuankang, Zheng Xinjie, Li Taixi, Niu kaifan, Wang Zhixiang, Song Juan, Duan Junli, Li Suiji, Lu Xia and Shen Chengxing
    Citation: Cardiovascular Diabetology 2023 22:190
    Content type: Research Published on:

  10. The relationship between stress hyperglycemia and long-term prognosis in acute decompensated heart failure (ADHF) patients is unknown. This study investigated the associations of stress hyperglycemia with mort...

    Authors: Qing Zhou, Jie Yang, Wenyao Wang, Chunli Shao, Xinwei Hua and Yi-Da Tang
    Citation: Cardiovascular Diabetology 2023 22:189
    Content type: Research Published on:

  11. Sodium-glucose co-transporter-2 inhibitors displayed cardiovascular benefits in type 2 diabetes mellitus in previous studies; however, there were some heterogeneities regarding respective cardiovascular outcom...

    Authors: Jaehyun Lim, You-Jung Choi, Bong Sung Kim, Tae-Min Rhee, Hyun-Jung Lee, Kyung-Do Han, Jun-Bean Park, Jin Oh Na, Yong-Jin Kim, Heesun Lee and Hyung-Kwan Kim
    Citation: Cardiovascular Diabetology 2023 22:188
    Content type: Research Published on:

  12. Elevated triglyceride levels are a clinically useful marker of remnant cholesterol. It is unknown whether triglycerides are associated with residual cardiovascular risk in CVD-naïve patients with newly diagnos...

    Authors: Frederik Pagh Bredahl Kristensen, Diana Hedevang Christensen, Martin Bødtker Mortensen, Michael Maeng, Johnny Kahlert, Henrik Toft Sørensen and Reimar Wernich Thomsen
    Citation: Cardiovascular Diabetology 2023 22:187
    Content type: Research Published on:

  13. Coronary computed tomography angiography (CCTA)-derived fractional flow reserve (CT-FFR) enables physiological assessment and risk stratification, which is of significance in diabetic patients with nonobstruct...

    Authors: Zinuan Liu, Yipu Ding, Guanhua Dou, Xi Wang, Dongkai Shan, Bai He, Jing Jing, Tao Li, Yundai Chen and Junjie Yang
    Citation: Cardiovascular Diabetology 2023 22:186
    Content type: Research Published on:

  14. Although sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated cardiovascular benefits in patients with type 2 diabetes mellitus, real-world evidence regarding their benefits to diabetic patient...

    Authors: Young Sang Lyu, Seok Oh, Jin Hwa Kim, Sang Yong Kim and Myung Ho Jeong
    Citation: Cardiovascular Diabetology 2023 22:185
    Content type: Research Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2023 22:242

  15. The relationship between sodium glucose co-transporter 2 inhibitors (SGLT2i) and trimethylamine N-oxide (TMAO) following acute myocardial infarction (AMI) is not yet explored.

    Authors: Faisal Aziz, Norbert J. Tripolt, Peter N. Pferschy, Ewald Kolesnik, Harald Mangge, Pero Curcic, Markus Hermann, Andreas Meinitzer, Dirk von Lewinski and Harald Sourij
    Citation: Cardiovascular Diabetology 2023 22:184
    Content type: Research Published on:

  16. To investigate the association of variability in metabolic parameters such as total cholesterol concentrations (TC), uric acid (UA), body mass index (BMI), visceral adiposity index (VAI) and systolic blood pre...

    Authors: Ning Chen, Yu-Hong Liu, Li-Kun Hu, Lin-Lin Ma, Yu Zhang, Xi Chu, Jing Dong and Yu-Xiang Yan
    Citation: Cardiovascular Diabetology 2023 22:183
    Content type: Research Published on:

  17. Type 2 diabetes mellitus (T2DM) patients are at high risk of cardiovascular (CV) events. Factor XI (FXI) is associated with arterial thromboembolism, including myocardial infarction (MI), stroke, and CV morta...

    Authors: Elżbieta Paszek, Maciej Polak, Agata Hanna Bryk-Wiązania, Małgorzata Konieczyńska and Anetta Undas
    Citation: Cardiovascular Diabetology 2023 22:182
    Content type: Research Published on:

  18. Both elevated inflammation and atherogenic dyslipidemia are prominent in young-onset diabetes and are increasingly identified as biologically intertwined processes that contribute to diabetogenesis. We aimed t...

    Authors: Yulong Lan, Dan Wu, Zhiwei Cai, Yuancheng Xu, Xiong Ding, Weiqiang Wu, Shaocong Lan, Lan Chen, Zheng Guo, Lois Balmer, Xingang Li, Manshu Song, Shouling Wu, Jingli Gao, Wei Wang and Youren Chen
    Citation: Cardiovascular Diabetology 2023 22:181
    Content type: Research Published on:

  19. The triglyceride-glucose (TyG) index and the stress hyperglycaemia ratio (SHR) are both positively associated with cardiovascular (CV) risk in patients with coronary heart disease. However, the prognostic valu...

    Authors: Yanjun Song, Kongyong Cui, Min Yang, Chenxi Song, Dong Yin, Qiuting Dong, Ying Gao and Kefei Dou
    Citation: Cardiovascular Diabetology 2023 22:180
    Content type: Research Published on:

  20. Knowledge of the characteristics of first-ever cardiovascular events in type 1 diabetes may impact primary prevention strategies. This study describes the first-ever manifestation of cardiovascular disease (CV...

    Authors: Gabriel Giménez-Pérez, Clara Viñals, Manel Mata-Cases, Bogdan Vlacho, Jordi Real, Josep Franch-Nadal, Emilio Ortega and Dídac Mauricio
    Citation: Cardiovascular Diabetology 2023 22:179
    Content type: Research Published on:

  21. Type 2 diabetes mellitus (T2DM) and anemia are related to some cardiovascular diseases and can predict poor outcomes. Both of them can damage the heart in their own ways, but their combined effects have not be...

    Authors: Wen-Lei Qian, Zhi-Gang Yang, Rui Shi, Ying-Kun Guo, Han Fang, Meng-ting Shen and Yuan Li
    Citation: Cardiovascular Diabetology 2023 22:178
    Content type: Research Published on:

  22. Recent studies revealed that alterations in glucose and lipid metabolism in idiopathic pulmonary arterial hypertension (IPAH) are associated with disease severity and poor survival. However, data regarding the...

    Authors: Kamil Jonas, Marcin Kurzyna, Ewa Mroczek, Łukasz Chrzanowski, Tatiana Mularek-Kubzdela, Ilona Skoczylas, Piotr Błaszczak, Grzegorz Grześk, Katarzyna Mizia-Stec, Beata Kuśmierczyk, Karol Kamiński, Ewa Lewicka, Małgorzata Peregud-Pogorzelska, Michał Tomaszewski, Wojciech Jacheć, Zbigniew Gąsior…
    Citation: Cardiovascular Diabetology 2023 22:177
    Content type: Research Published on:

  23. The insulin-like growth factors (IGF) play a crucial role in regulating cellular proliferation, apoptosis, and key metabolic pathways. The ratio of IGF-1 to IGF binding protein-3 (IGFBP-3) is an important fact...

    Authors: Reza Mohebi, Yuxi Liu, Michael K. Hansen, Yshai Yavin, Naveed Sattar, Carol A. Pollock, Javed Butler, Meg Jardine, Serge Masson, Hiddo J. L. Heerspink and James L. Januzzi Jr
    Citation: Cardiovascular Diabetology 2023 22:176
    Content type: Research Published on:

  24. This ANAFIE Registry sub-analysis investigated 2-year outcomes and oral anticoagulant (OAC) use stratified by glycated hemoglobin (HbA1c) levels among Japanese patients aged ≥ 75 years with non-valvular atrial...

    Authors: Yasuo Terauchi, Hiroshi Inoue, Takeshi Yamashita, Masaharu Akao, Hirotsugu Atarashi, Takanori Ikeda, Yukihiro Koretsune, Ken Okumura, Shinya Suzuki, Hiroyuki Tsutsui, Kazunori Toyoda, Atsushi Hirayama, Masahiro Yasaka, Takenori Yamaguchi, Satoshi Teramukai, Tetsuya Kimura…
    Citation: Cardiovascular Diabetology 2023 22:175
    Content type: Research Published on:

  25. Type 2 diabetes (T2D) is expected to worsen the prognosis of inpatients with heart failure (HF) but the evidence from observational studies is inconsistent. We aimed to compare mortality outcomes and life expe...

    Authors: Dante Salvador Jr, Arjola Bano, Faina Wehrli, Valentina Gonzalez-Jaramillo, Markus Laimer, Lukas Hunziker and Taulant Muka
    Citation: Cardiovascular Diabetology 2023 22:174
    Content type: Research Published on:

  26. Hyperglycaemia is frequent in acute ischemic stroke and denotes a bad prognosis, even in the absence of pre-existing diabetes. However, in clinical trials treatment of elevated glucose levels with insulin did ...

    Authors: Sina Rhein, Julica Inderhees, Oliver Herrmann, Alaa Othman, Kimberly Begemann, Thomas Fleming, Peter P. Nawroth, Karel D. Klika, Rakad Isa, Inke R. König, Georg Royl and Markus Schwaninger
    Citation: Cardiovascular Diabetology 2023 22:173
    Content type: Research Published on:

  27. Higher chemokine C-X-C motif ligand 5 (CXCL5) level was observed in type 2 diabetes mellitus (DM) patients; however, its role in diabetic vasculopathy was not clarified. This study aimed to explore the impacts...

    Authors: Ching Chen, Liang-Yu Lin, Jaw-Wen Chen and Ting-Ting Chang
    Citation: Cardiovascular Diabetology 2023 22:172
    Content type: Research Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2023 22:196

  28. The triglyceride–glucose (TyG) index has been demonstrated to be a reliable surrogate marker of insulin resistance (IR) and an effective predictive index of cardiovascular (CV) disease risk. However, its long-...

    Authors: You Zhou, Chi Wang, Hebin Che, Liting Cheng, Di Zhu, Chongyou Rao, Qin Zhong, Zongren Li, Xiao Wang, Zisheng Wu and Kunlun He
    Citation: Cardiovascular Diabetology 2023 22:171
    Content type: Research Published on:

    The Correction to this article has been published in Cardiovascular Diabetology 2023 22:250

  29. The TyG index is an indicator of insulin resistance (IR), which is associated with the development and prognosis of cardiovascular disease. This study aimed to summarize the relationship between the TyG index ...

    Authors: Shichu Liang, Cui Wang, Jing Zhang, Zhiyue Liu, Yanlin Bai, Zhonglan Chen, He Huang and Yong He
    Citation: Cardiovascular Diabetology 2023 22:170
    Content type: Research Published on:

  30. Triglyceride-rich lipoproteins (TRL) and low-density lipoproteins (LDL) are associated positively whereas high-density lipoproteins (HDL) are associated inversely with the development of new-onset type 2 diabe...

    Authors: Arno R. Bourgonje, Margery A. Connelly, Harry van Goor, Peter R. van Dijk and Robin P. F. Dullaart
    Citation: Cardiovascular Diabetology 2023 22:169
    Content type: Research Published on:

  31. L-type Ca2+ channel CaV1.2 is essential for cardiomyocyte excitation, contraction and gene transcription in the heart, and abnormal functions of cardiac CaV1.2 channels are presented in diabetic cardiomyopathy. H...

    Authors: Pengpeng Li, Dongxia Qin, Tiange Chen, Wei Hou, Xinyu Song, Shumin Yin, Miaomiao Song, W.C. Hewith A. Fernando, Xiaojie Chen, Yu Sun and Juejin Wang
    Citation: Cardiovascular Diabetology 2023 22:168
    Content type: Research Published on:

  32. Glycemic variability plays an important role in the development of cardiovascular disease (CVD). This study aims to determine whether long-term visit-to-visit glycemic variability is associated with aortic sti...

    Authors: Qianhua Fang, Juan Shi, Jia Zhang, Ying Peng, Cong Liu, Xing Wei, Zhuomeng Hu, Lin Sun, Jie Hong, Weiqiong Gu, Weiqing Wang and Yifei Zhang
    Citation: Cardiovascular Diabetology 2023 22:167
    Content type: Research Published on:

  33. SGTL2-inhibitors are a cornerstone in the treatment of heart failure, but data on patients with acute myocardial infarction (AMI) is limited. The EMMY trial was the first to show a significant reduction in NTp...

    Authors: Martin Benedikt, Harald Mangge, Faisal Aziz, Pero Curcic, Sabine Pailer, Markus Herrmann, Ewald Kolesnik, Norbert J. Tripolt, Peter N. Pferschy, Markus Wallner, Andreas Zirlik, Harald Sourij and Dirk von Lewinski
    Citation: Cardiovascular Diabetology 2023 22:166
    Content type: Research Published on:

  34. Stress hyperglycemia was positively associated with poor prognosis in individuals with acute myocardial infarction (AMI). However, admission glucose and stress hyperglycemia ratio (SHR) may not be the best ind...

    Authors: Kongyong Cui, Rui Fu, Jingang Yang, Haiyan Xu, Dong Yin, Weihua Song, Hongjian Wang, Chenggang Zhu, Lei Feng, Zhifang Wang, Qingsheng Wang, Ye Lu, Kefei Dou and Yuejin Yang
    Citation: Cardiovascular Diabetology 2023 22:165
    Content type: Research Published on:

  35. In recent years, GLP-1 receptor agonists (GLP-1RA), and SGLT-2 inhibitors (SGLT-2i) have become available, which have become valuable additions to therapy for type 2 diabetes as they are associated with low ri...

    Authors: Cristina Panico, Benedetta Bonora, Antonella Camera, Nino Cristiano Chilelli, Giuliana Da Prato, Giuseppe Favacchio, Valeria Grancini, Veronica Resi, Maurizio Rondinelli, Emanuela Zarra and Basilio Pintaudi
    Citation: Cardiovascular Diabetology 2023 22:164
    Content type: Review Published on:

  36. This study aimed to examine the association between the incident onset of T2DM and 5- and 10-year risks of CVD and HF in people with IGT identified in primary care in South and West Auckland, New Zealand (NZ) ...

    Authors: Dahai Yu, Bingjie Qu, Uchechukwu Levi Osuagwu, Karen Pickering, John Baker, Richard Cutfield MBChB, Yamei Cai, Brandon J Orr-Walker, Gerhard Sundborn, Zhanzheng Zhao and David Simmons
    Citation: Cardiovascular Diabetology 2023 22:163
    Content type: Research Published on:

  38. Insulin resistance (IR) has been confirmed that getting involved in the pathophysiological process of cardiovascular diseases (CVD). Recently, increasing evidence suggests metabolic score for insulin resistanc...

    Authors: Zenglei Zhang, Lin Zhao, Yiting Lu, Xu Meng and Xianliang Zhou
    Citation: Cardiovascular Diabetology 2023 22:161
    Content type: Research Published on:

  39. Numerous studies have investigated the potential association of sodium-glucose co-transporter-2 inhibitors (SGLT2-Is) with an increased risk of lower limb amputations (LLAs), but have produced conflicting resu...

    Authors: Nikki C. C. Werkman, Johanna H. M. Driessen, Coen D. A. Stehouwer, Peter Vestergaard, Nicolaas C. Schaper, Joop P. van den Bergh and Johannes T. H. Nielen
    Citation: Cardiovascular Diabetology 2023 22:160
    Content type: Research Published on:

  40. Authors: Ki‑Bum Won, Seung‑Ho Hur, Yun‑Kyeong Cho, Hyuck‑Jun Yoon, Chang‑Wook Nam, Kwon‑Bae Kim, Jang‑Ho Bae, Dong‑Ju Choi, Young‑Keun Ahn, Jong‑Seon Park, Hyo‑Soo Kim, Rak‑Kyeong Choi, Donghoon Choi, Joon‑Hong Kim, Kyoo‑Rok Han, Hun‑Sik Park…
    Citation: Cardiovascular Diabetology 2023 22:159
    Content type: Correction Published on:

    The original article was published in Cardiovascular Diabetology 2015 14:141

  41. Diabetic cardiovascular autonomic neuropathy (CAN) and distal symmetrical polyneuropathy (DSPN) are severe diabetic complications. Collagen type VI (COL6) and III (COL3) have been associated with nerve functio...

    Authors: Christian S. Hansen, Daniel G. K. Rasmussen, Tine W. Hansen, Signe Holm Nielsen, Simone Theilade, Morten A. Karsdal, Federica Genovese and Peter Rossing
    Citation: Cardiovascular Diabetology 2023 22:158
    Content type: Research Published on:

  42. Although there is numerous evidence on the epidemiological risk factors for insulin resistance (IR)-related metabolic diseases, there is still insufficient evidence to explore the non-linear association of Ath...

    Authors: Bei Yin, Zihong Wu, Yaqing Xia, Shunqiang Xiao, Lingling Chen and Yousheng Li
    Citation: Cardiovascular Diabetology 2023 22:157
    Content type: Research Published on:

  43. The association of the triglyceride-glucose (TyG) index with severe consciousness disturbance and in-hospital mortality in patients with cerebrovascular disease in the intensive care unit (ICU) is unclear. Thi...

    Authors: Ting Chen, Yuan Qian and Xingli Deng
    Citation: Cardiovascular Diabetology 2023 22:156
    Content type: Research Published on:

  45. Type 2 diabetes mellitus (T2DM) frequently coexists with obstructive coronary artery disease (OCAD), which are at increased risk for cardiovascular morbidity and mortality. This study aimed to investigate the ...

    Authors: Jin Wang, Zhi-Gang Yang, Ying-Kun Guo, Yu Jiang, Wei-Feng Yan, Wen-Lei Qian, Han Fang, Chen-Yan Min and Yuan Li
    Citation: Cardiovascular Diabetology 2023 22:154
    Content type: Research Published on:

  46. Recent large clinical trials have demonstrated cardiovascular benefits of similar overall magnitude for sodium–glucose cotransporter-2 inhibitor (SGLT-2i) and glucagon-like peptide-1 receptor agonist (GLP-1RA)...

    Authors: Minji Sohn, Johannes W. Dietrich, Michael A. Nauck and Soo Lim
    Citation: Cardiovascular Diabetology 2023 22:153
    Content type: Research Published on:

  47. The cardiovascular (CV) benefits of sodium-glucose transport protein 2 inhibitors have been attributed, in part, to cardiac reverse remodelling. The EMPA-HEART CardioLink-6 study reported that sodium-glucose c...

    Authors: Pankaj Puar, Makoto Hibino, C. David Mazer, Andrew T. Yan, Arjun K. Pandey, Adrian Quan, Hwee Teoh, David A. Hess, Raj Verma, Kim A. Connelly and Subodh Verma
    Citation: Cardiovascular Diabetology 2023 22:152
    Content type: Research Published on:

  48. The potential predictive significance of atherogenic index of plasma (AIP) for cardiovascular outcomes in patients with acute coronary syndrome (ACS) and who have undergone percutaneous coronary intervention (...

    Authors: Yue Wang, Shen Wang, Shuaifeng Sun, Fadong Li, Wenxin Zhao, Hongxia Yang and Xiaofan Wu
    Citation: Cardiovascular Diabetology 2023 22:150
    Content type: Research Published on:

  49. Diabetic foot is a significant cause of morbidity in diabetic patients, with a rate that is approximately twice that of patients without foot ulcers. “Metabolic memory” represents the epigenetic changes induce...

    Authors: Alessandro Del Cuore, Rosaria Maria Pipitone, Alessandra Casuccio, Marco Maria Mazzola, Maria Grazia Puleo, Gaetano Pacinella, Renata Riolo, Carlo Maida, Tiziana Di Chiara, Domenico Di Raimondo, Rossella Zito, Giulia Lupo, Luisa Agnello, Gabriele Di Maria, Marcello Ciaccio, Stefania Grimaudo…
    Citation: Cardiovascular Diabetology 2023 22:148
    Content type: Research Published on:

  50. Impaired kidney function and albuminuria are associated with increased risk of heart failure (HF) in patients with type 2 diabetes (T2D). We investigated whether rapid kidney function decline over time is an a...

    Authors: Carlos Roberto Bueno Junior, Arjola Bano, Yaling Tang, Xiuqin Sun, Alex Abate, Elizabeth Hall, Joanna Mitri, Mario Luca Morieri, Hetal Shah and Alessandro Doria
    Citation: Cardiovascular Diabetology 2023 22:131
    Content type: Research Published on:
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