Table 1 Baseline characteristics of AMI patients by tertiles of systemic-immune inflammation index
Clinical characteristics | Overall (N = 2111) | Tertiles of systemic-immune inflammation index |  | ||
|---|---|---|---|---|---|
Tertile 1 (N = 702) | Tertile 2 (N = 706) | Tertile 3 (N = 703) | P-value | ||
 < 613.57 | 613.57–1136.56 |  ≥ 1136.56 |  | ||
Age, years | 65.2 ± 12.2 | 65.4 ± 12.0 | 64.6 ± 12.4 | 65.5 ± 12.2 | 0.339 |
Male sex | 1637 (77.5) | 534 (76.1) | 552 (78.2) | 551 (78.4) | 0.515 |
Current smoker | 953 (45.1) | 303 (43.2) | 343 (48.6) | 307 (43.7) | 0.078 |
Comorbidities | Â | Â | Â | Â | Â |
 Hypertension | 1342 (63.6) | 441 (62.8) | 444 (62.9) | 457 (65.0) | 0.628 |
 Diabetes mellitus | 789 (37.4) | 277 (39.5) | 258 (36.5) | 254 (36.1) | 0.377 |
 Dyslipidemia | 565 (26.8) | 183 (26.1) | 187 (26.5) | 195 (27.7) | 0.763 |
 Chronic kidney disease | 165 (7.8) | 40 (5.7) | 61 (8.6) | 64 (9.1) | 0.036 |
 History of HF | 105 (5.0) | 28 (4.0) | 33 (4.7) | 44 (6.3) | 0.133 |
 History of MI | 137 (6.5) | 57 (8.1) | 41 (5.8) | 39 (5.6) | 0.098 |
 History of PCI | 187 (8.9) | 84 (12.0) | 49 (6.9) | 54 (7.7) | 0.002 |
 History of stroke/TIA | 236 (11.2) | 64 (9.1) | 87 (12.3) | 85 (12.1) | 0.104 |
Admission presentation | Â | Â | Â | Â | Â |
 STEMI | 1272 (60.3) | 327 (46.6) | 439 (62.2) | 506 (72.0) |  < 0.001 |
 Anterior locationa | 654 (51.4) | 155 (47.4) | 234 (53.3) | 265 (52.4) | 0.401 |
 Systolic BP, mmHg | 138.5 ± 23.9 | 139.2 ± 22.7 | 139.2 ± 23.4 | 136.9 ± 25.4 | 0.123 |
 Heart rate, bpm | 79.6 ± 16.7 | 76.3 ± 15.7 | 79.6 ± 15.4 | 83.0 ± 18.2 |  < 0.001 |
 Killip class > I | 279 (13.2) | 68 (9.7) | 76 (10.8) | 135 (19.2) |  < 0.001 |
Laboratory indices | Â | Â | Â | Â | Â |
 C-reactive protein, mg/L | 5.38 (3.17–17.20) | 3.97 (3.02–12.80) | 5.69 (3.27–17.26) | 6.86 (3.17–25.90) |  < 0.001 |
 Peak TnT, ng/mL | 2.97 (0.78–7.98) | 1.55 (0.43–4.88) | 2.90 (0.97–7.27) | 5.36 (1.63–10.00) |  < 0.001 |
 Serum creatinine, mg/dL | 0.95 ± 0.33 | 0.93 ± 0.31 | 0.95 ± 0.34 | 0.98 ± 0.33 | 0.018 |
 Leukocyte count, 109/L | 9.54 ± 3.04 | 7.78 ± 2.08 | 9.30 ± 2.54 | 11.60 ± 3.13 |  < 0.001 |
 Neutrophil, count 109/L | 7.14 ± 2.92 | 4.88 ± 1.45 | 6.88 ± 2.00 | 9.66 ± 2.82 |  < 0.001 |
 Lymphocyte count, 109/L | 1.72 ± 0.79 | 2.22 ± 0.88 | 1.72 ± 0.62 | 1.22 ± 0.50 |  < 0.001 |
 Platelet count, 109/L | 207.1 ± 59.6 | 181.5 ± 48.7 | 206.8 ± 54.8 | 233.1 ± 63.0 |  < 0.001 |
 Log-transformed SII | 2.93 ± 0.31 | 2.60 ± 0.15 | 2.91 ± 0.07 | 3.27 ± 0.18 |  < 0.001 |
Angiographic data | Â | Â | Â | Â | Â |
 Primary PCI | 1778 (84.2) | 567 (80.8) | 609 (86.3) | 602 (85.6) | 0.008 |
 Infarct-related arteryb |  |  |  |  | 0.075 |
 Left anterior descending | 626 (51.6) | 146 (47.1) | 232 (54.7) | 248 (51.8) |  |
 Right coronary artery | 455 (37.5) | 127 (41.0) | 140 (33.0) | 188 (39.2) | |
 Left circumflex | 132 (10.9) | 37 (11.9) | 52 (12.3) | 43 (9.0) | |
Echocardiographic data | Â | Â | Â | Â | Â |
 LAD, mm | 38.1 ± 4.6 | 38.3 ± 4.4 | 38.2 ± 4.7 | 37.8 ± 4.7 | 0.171 |
 LVESD, mm | 31.0 ± 5.5 | 30.7 ± 5.4 | 30.7 ± 5.3 | 31.5 ± 5.6 | 0.015 |
 LVEDD, mm | 45.6 ± 4.8 | 45.7 ± 4.8 | 45.5 ± 4.6 | 45.6 ± 4.9 | 0.889 |
 LVEF, % | 50.5 ± 10.5 | 52.7 ± 9.8 | 51.1 ± 10.2 | 47.7 ± 11.0 |  < 0.001 |
Medication at discharge | Â | Â | Â | Â | Â |
 Aspirin | 1946 (92.2) | 633 (90.2) | 662 (93.8) | 651 (92.6) | 0.037 |
 ACEI/ARB/ARNI | 1262 (59.8) | 445 (63.4) | 429 (60.8) | 388 (55.2) | 0.006 |
 β-blocker | 1528 (72.4) | 485 (69.1) | 511 (72.4) | 532 (75.7) | 0.022 |
 Statin | 2026 (96.0) | 677 (96.4) | 679 (96.2) | 670 (95.3) | 0.528 |
 Oral anticoagulants | 12 (0.6) | 6 (0.9) | 2 (0.3) | 4 (0.6) | 0.291 |
 Diuretics | 302 (14.3) | 79 (11.3) | 102 (14.5) | 121 (17.2) | 0.006 |
 Antidiabetic agents | 636 (30.1) | 220 (31.3) | 205 (29.0) | 211 (30.0) | 0.642 |
 Insulin | 255 (12.1) | 68 (9.7) | 84 (11.9) | 103 (14.7) | 0.017 |
  Metformin | 231 (10.9) | 88 (12.5) | 66 (9.4) | 77 (11.0) | 0.161 |
  Sulfonylureas | 213 (10.1) | 83 (11.8) | 71 (10.1) | 59 (8.4) | 0.104 |
  Glinides | 41 (1.9) | 17 (2.4) | 11 (1.6) | 13 (1.9) | 0.490 |
  Thiazolidinediones | 19 (0.9) | 9 (1.3) | 6 (0.9) | 4 (0.6) | 0.354 |