Plasma metabolite profile of legume consumption and future risk of type 2 diabetes and cardiovascular disease

Table 2 Pearson correlation coefficients between metabolomics signatures and legume consumption

	Baseline data				Internal validation population (Year 1 data in PREDIMED)
	Pearson correlation with metabolomic signature (95% CI)	Total No. Metabolites^a	No. of metabolites with positive coefficients	No. of metabolites with negative coefficients	Pearson correlation (95% CI)
Total legumes, g/d^b	0.17 (0.12, 0.23)	40	18	22	0.15 (0.10, 0.19)

CI confidence interval, PREDIMED PREvención con DIeta MEDiterránea
^aMetabolite coefficients obtained 10 times in the cross-validation procedure for the elastic net continuous approach. Results using the lambda.min option
^bAdjusted for total energy intake using the residual method

ISSN: 1475-2840