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Table 1 Baseline characteristics stratified by the occurrence of CV events

From: Triglyceride-glucose index as a suitable non-insulin-based insulin resistance marker to predict cardiovascular events in patients undergoing complex coronary artery intervention: a large-scale cohort study

 

Overall (n = 9154)

Without CV events (n = 8830)

CV events (n = 324)

P value

TyG index

8.92 ± 0.56

8.92 ± 0.56

9.02 ± 0.60

0.002

TG/HDL-C ratio

3.83 ± 2.46

3.83 ± 2.46

3.94 ± 2.53

0.432

METS-IR

41.68 ± 7.02

41.69 ± 7.01

41.57 ± 7.22

0.762

Age, years

59.83 ± 9.64

59.73 ± 9.62

62.66 ± 9.88

< 0.001

Male

7220 (78.9)

6975 (79.0)

245 (75.6)

0.164

BMI, kg/m2

25.98 ± 3.16

26.00 ± 3.16

25.58 ± 3.09

0.019

Clinical presentation

0.002

 CCS

3582 (39.1)

3482 (39.4)

100 (30.9)

 

 ACS

5572 (60.9)

5348 (60.6)

224 (69.1)

 

Family history of CAD

1078 (11.8)

1034 (11.7)

44 (13.6)

0.348

Prior MI

2322 (25.4)

2210 (25.0)

112 (34.6)

< 0.001

Prior PCI

2042 (22.3)

1952 (22.1)

90 (27.8)

0.019

Prior CABG

302 (3.3)

282 (3.2)

20 (6.2)

0.005

Hypertension

7681 (83.9)

7397 (83.8)

284 (87.7)

0.073

Diabetes

4202 (45.9)

4033 (45.7)

169 (52.2)

0.025

Prior stroke

1261 (13.8)

1204 (13.6)

57 (17.6)

0.051

PAD

641 (7.0)

609 (6.9)

32 (9.9)

0.051

Current smoker

2880 (31.5)

2770 (31.4)

110 (34.0)

0.357

CKD

143 (1.6)

134 (1.5)

9 (2.8)

0.117

SBP, mmHg

131.33 ± 17.59

131.24 ± 17.57

133.65 ± 17.90

0.016

DBP, mmHg

77.38 ± 10.85

77.40 ± 10.83

76.91 ± 11.26

0.427

LVEF, %

61.85 ± 6.68

61.92 ± 6.58

59.78 ± 8.76

< 0.001

Laboratory tests

 Creatinine, μmol/L

83.41 ± 17.17

83.28 ± 16.88

87.02 ± 23.33

< 0.001

 eGFR, mL/min/1.73m2

85.37 ± 17.50

85.53 ± 17.44

81.01 ± 18.40

< 0.001

 HbA1c, %

6.53 ± 1.27

6.53 ± 1.26

6.78 ± 1.39

< 0.001

 FPG, mmol/L

6.59 ± 2.42

6.56 ± 2.39

7.23 ± 3.12

< 0.001

 TG, mmol/L

1.66 ± 0.81

1.66 ± 0.81

1.69 ± 0.82

0.468

 TC, mmol/L

4.04 ± 1.05

4.04 ± 1.05

4.02 ± 1.04

0.730

 HDL-C, mmol/L

1.10 ± 0.29

1.10 ± 0.29

1.09 ± 0.29

0.595

 LDL-C, mmol/L

2.45 ± 0.91

2.46 ± 0.92

2.43 ± 0.88

0.681

 hsCRP, mg/L

2.63 ± 3.05

2.61 ± 3.05

3.06 ± 3.21

< 0.001

Procedural data

 SYNTAX score

16.45 ± 5.51

16.43 ± 5.49

17.11 ± 5.91

0.028

 Left main disease

1761 (19.2)

1688 (19.1)

73 (22.5)

0.144

 Three-vessel disease

5057 (55.2)

4870 (55.2)

187 (57.7)

0.393

 CTO lesion

1204 (13.2)

1159 (13.1)

45 (13.9)

0.752

 Thrombotic lesion

118 (1.3)

113 (1.3)

5 (1.5)

0.871

 Ostial lesion

1438 (15.7)

1377 (15.6)

61 (18.8)

0.135

 Type B2/C lesion

7222 (78.9)

6963 (78.9)

259 (79.9)

0.690

 Severe calcification

691 (7.5)

651 (7.4)

40 (12.3)

0.001

 Number of treated lesions

1.90 ± 0.81

1.90 ± 0.81

1.88 ± 0.85

0.669

 Total stent number

4.33 ± 2.91

4.35 ± 2.93

3.96 ± 2.37

0.019

 Total stent length

63.69 ± 33.43

63.78 ± 33.49

61.23 ± 31.86

0.178

Medications

 Aspirin

6775 (74.0)

6541 (74.1)

234 (72.2)

0.495

 Clopidogrel

7693 (84.0)

7418 (84.0)

275 (84.9)

0.733

 Statins

8882 (97.0)

8568 (97.0)

314 (96.9)

1.000

 ACEI/ARB

2378 (26.0)

2299 (26.0)

79 (24.4)

0.547

 β blocker

8185 (89.4)

7892 (89.4)

293 (90.4)

0.607

 Antidiabetic drugs

3227 (35.3)

3099 (35.1)

128 (39.5)

0.116

  1. Values are mean ± standard deviation or n (%)
  2. CV cardiovascular, TyG triglyceride-glucose, TG triglyceride, HDL-C high-density lipoprotein cholesterol, METS-IR metabolic score for insulin resistance, BMI body mass index, CCS chronic coronary syndrome, ACS acute coronary syndrome, CAD coronary artery disease, MI myocardial infarction, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, PAD peripheral artery disease, CKD chronic kidney disease, SBP systolic blood pressure, DBP diastolic blood pressure, LVEF left ventricular ejection fraction, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, FPG fasting plasma glucose, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, hsCRP high sensitivity C-reactive protein, SYNTAX synergy between PCI with taxus and cardiac surgery, CTO chronic total occlusion, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker