Reduced thoracic skeletal muscle size is associated with adverse outcomes in diabetes patients with heart failure and reduced ejection fraction: quantitative analysis of sarcopenia by using cardiac MRI

Table 3 Linear regression analysis for factors associated with NT-proBNP

Variables	Univariable coefficient B (one unit increase for continuous variables/yes or no for categorical variables)	Univariable standardized coefficient β (compare the effect estimates)	Multivariable coefficient B (one unit increase for continuous variables/yes or no for categorical variables)	Multivariable standardized coefficient β (adjusted R² = 0.31) (compare the effect estimates)
Age	0.01	0.20†	0.004	0.08†
Male sex	-0.08	-0.07
BMI	-0.02	-0.12
NYHA functional class ≥ III	0.46	0.27†	0.456	0.25†
eGFR	-0.01	-0.39†	-0.007	-0.32†
LVEF	-0.01	-0.13†	-0.006	-0.11†
LVM index	0.01	0.31†	0.006	0.20†
Thoracic SMI	-0.02	-0.34†	-0.007	-0.25†

Abbreviations: NT-proBNP, amino-terminal pro-B-type natriuretic peptide; BMI, body mass index; NYHA, New York Heart Association; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; LVM, left ventricular mass; SMI, skeletal muscle index
† indicates P-value < 0.05. NT-proBNP is log-transformed before being included in the regression analysis

ISSN: 1475-2840