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Table 3 Differences between the cluster categories (HVA and EVA) in the quantitative risk factors

From: Validation of an early vascular aging construct model for comprehensive cardiovascular risk assessment using external risk indicators for improved clinical utility: data from the EVasCu study

Variables

HVA

EVA

p value

Median

IQR

Median

IQR

Sociodemographic factors

Age, years

35.0

24.3–44.0

53.0

48.0–58.0

< 0.001

Adiposity factors

BMI, kg/m2

23.6

21.3–23.8

25.9

23.3–29.3

< 0.001

Waist circumference, cm

78.4

70.3–86.2

87.2

79.3–96.9

< 0.001

Fat percentage. %

24.9

19.2–31.8

29.9

23.9–37.5

< 0.001

Glycemic and inflammatory factors

Glucose, mg/dL

87.0

81.0-90.8

93.0

86.0–99.0

< 0.001

Insulin, mg/dL

6.6

4.5–9.4

7.1

4.8–11.6

0.034

CRP, mg/L

0.8

0.4–1.5

1.0

0.5–1.5

0.031

Lipid profile factors

Total cholesterol, mg/dL

176.0

152.3-202.7

197.5

176.5-223.3

< 0.001

HDL, mg/dL

61.5

52.0–70.0

61.0

50.5–69.1

0.498

LDL, mg/dL

108.0

87.0-132.0

127.0

109.0-152.0

< 0.001

Triglycerides, mg/dL

68.5

56.0–91.0

81.5

63.8–114.0

< 0.001

Vascular factors

AIx-75, %

16.5

5.0–24.0

19.0

10.0–29.0

< 0.001

ABI

1.1

1.1–1.2

1.1

1.1–1.2

0.115

CAVI, m/s

6.8

6.1–7.3

7.4

7.0-8.4

< 0.001

IMT, mm

0.2

0.1–0.3

0.2

0.2–0.3

0.015

Blood pressure factors

SBP, mmHg

111.0

104.0-120-0

122.0

110.0-134.5

< 0.001

DBP, mmHg

68.0

62.0–74.0

73.0

65.0–82.0

< 0.001

  1. HVA, healthy vascular aging; EVA, early vascular aging; IQR: interquartile range; BMI, body mass index; CRP, c-reactive protein; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; AIx@75, augmentation index; ABI, ankle-brachial index; CAVI, cardio-ankle vascular index; IMT: intima media thickness; SBP, systolic blood pressure; DBP, diastolic blood pressure