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Table 2 Baseline characteristics and incidence of CVDs according to TyG index trajectories

From: Relationship between triglyceride-glucose index baselines and trajectories with incident cardiovascular diseases in the elderly population

Characteristics

Total

Trajectory 1

Trajectory 2

Trajectory 3

Trajectory 4

Trajectory 5

P value

N

20,185

4073

10,948

3980

709

475

 

TyG indexa

8.4 ± 0.6

7.7 ± 0.3

8.4 ± 0.3

9.0 ± 0.4

9.1 ± 1.2

8.1 ± 0.9

 < 0.001

Age,yearsa

76.9 ± 6.3

77.7 ± 6.1

77.1 ± 6.3

75.8 ± 6.1

75.9 ± 6.6

75.6 ± 6.6

 < 0.001

Male, n(%)

8,411 (41.7)

2,319 (56.9)

4,321 (39.5)

1,206 (30.3)

333 (47.0)

232 (48.8)

 < 0.001

BMI, kg/m2a

24.7 ± 4.2

23 ± 3.2

24.9 ± 3.4

26.3 ± 4.9

24.6 ± 9.9

24.0 ± 3.8

 < 0.001

Current smoking, n(%)

13,916(68.9)

3125 (76.7)

7867 (71.9)

2185 (54.9)

449 (63.3)

290 (61.1)

 < 0.001

Current drinking, n(%)

16,768(83.1)

3933 (96.6)

9302 (85.0)

2503 (62.9)

619 (87.3)

411 (86.5)

 < 0.001

Education, n(%)

      

 < 0.001

 < High school

18,931 (93.8)

3923 (96.3)

10,287 (94.0)

3595 (90.3)

672 (94.8)

454 (95.6)

 

High school

878 (4.3)

78 (1.9)

421 (3.8)

335 (8.4)

27 (3.8)

17 (3.6)

 

 > High school

376 (1.9)

72 (1.8)

240 (2.2)

50 (1.3)

10 (1.4)

4 (0.8)

 

Salt craving, n(%)

876 (4.3)

230 (5.6)

494 (4.5)

97 (2.4)

32 (4.5)

23 (4.8)

 < 0.001

Oil craving, n(%)

138 (0.7)

31 (0.8)

63 (0.6)

34 (0.9)

5 (0.7)

5 (1.1)

0.297

SBP, mmHga

117.2 ± 29.0

115.2 ± 18.1

116.6 ± 26.7

121.1 ± 39.9

115.4 ± 36.3

119.4 ± 33.6

 < 0.001

DBP, mmHga

76.0 ± 15.7

76.5 ± 8.9

76.1 ± 14.2

75.1 ± 22.4

74.4 ± 20.7

76.6 ± 18.7

 < 0.001

TC, mmol/Lb

5.2 (4.5, 5.9)

4.7 (4.1, 5.3)

5.2 (4.6, 5.9)

5.5 (4.6, 6.2)

5.2 (4.2, 6.2)

4.8 (4.1, 5.6)

 < 0.001

LDL-C, mmol/Lb

2.6 (2.1, 3.1)

2.3 (1.9, 2.8)

2.7 (2.2, 3.1)

2.8 (2.4, 3.3)

2.6 (2.0, 3.1)

2.5 (1.8, 3.0)

 < 0.001

HDL-C, mmol/Lb

1.5 (1.2, 1.7)

1.5 (1.3, 1.7)

1.5 (1.3, 1.7)

1.5 (1.2, 1.7)

1.4 (1.1, 1.7)

1.4 (1.1, 1.7)

 < 0.001

FBG, mmol/La

4.4 ± 1.3

3.9 ± 0.3

4.2 ± 0.7

5.3 ± 1.8

5.0 ± 3.9

4.3 ± 2.2

 < 0.001

TG, mmol/Lb

1.2 (0.9, 1.7)

0.7 (0.6, 0.9)

1.3 (1.0, 1.6)

2.0 (1.5, 2.6)

2.8 (1.1, 4.9)

1.0 (0.8, 1.5)

 < 0.001

Hypertension, n(%)

5521 (27.4)

760 (18.7)

2764 (25.2)

1611 (40.5)

213 (30.0)

173 (36.4)

 < 0.001

Diabetes, n(%)

771 (3.8)

7 (0.2)

151 (1.4)

507 (12.7)

85 (12.0)

21 (4.4)

 < 0.001

Dyslipidemia, n(%)

5999 (29.7)

512 (12.6)

2745 (25.1)

2175 (54.6)

459 (64.7)

108 (22.7)

 < 0.001

CVDs, n(%)

11,099 (55.0)

2068 (50.8)

6184 (56.5)

2253 (56.6)

364 (51.3)

230 (48.4)

 < 0.001

RHD, n(%)

60 (0.3)

17 (0.4)

28 (0.3)

11 (0.3)

2 (0.3)

2 (0.4)

0.570

CHD, n(%)

4170 (20.7)

686 (16.8)

2380 (21.7)

917 (23.0)

123 (17.3)

64 (13.5)

 < 0.001

CVD, n(%)

5598 (27.7)

1040 (25.5)

3143 (28.7)

1122 (28.2)

174 (24.5)

119 (25.1)

 < 0.001

PAD, n(%)

984 (4.9)

225 (5.5)

506 (4.6)

166 (4.2)

52 (7.3)

35 (7.4)

 < 0.001

VTE, n(%)

287 (1.4)

100 (2.5)

127 (1.2)

37 (0.9)

13 (1.8)

10 (2.1)

 < 0.001

  1. Trajectory 1, Low gradual increase trajectory; Trajectory 2, Medium stable trajectory; Trajectory 3, High gradual increase trajectory; Trajectory 4, Increase followed by decrease trajectory; Trajectory 5, Decrease followed by increase trajectory; TyG index, triglyceride–glucose index; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; FBG, fasting blood glucose; TG, triglyceride; CVDs, cardiovascular diseases; RHD, rheumatic heart disease; CHD, coronary heart disease; CVD, cerebrovascular disease; PAD, peripheral artery disease; VTE, deep vein thrombosis and pulmonary embolism
  2. aData are mean ± SD
  3. bData are median(IQR)
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Cardiovascular Diabetology

ISSN: 1475-2840