Table 2 Liver fat content and noninvasive scores of liver fibrosis in GEPSAD
Characteristic | All | LFC ≤ 5.56% | LFC > 5.56% |
|---|---|---|---|
No. subjects | 255 | 96 | 159 |
Liver fat content using MRI-PDFF | |||
Liver fat content (%) | 8.96 [3.32–16.6] | 2.70 [1.58–4.11] | 13.9 [9.42–21.2]*** |
> 5.56%, % (n) | 62.4 (159) | 0.0 (0) | 100 (159)*** |
Noninvasive scores of fibrosis | |||
FIB-4 | 0.875 [0.594–1.345] | 0.918 [0.603–1.359] | 0.818 [0.576–1.344] |
< 1.30, % (n) | 72.4 (181) | 74.5 (70) | 71.2 (111) |
≥ 2.67, % (n) | 3.6 (9) | 4.3 (4) | 3.2 (5) |
NFS | -0.163 ± 1.220 | -0.078 [-0.869-0.669] | 0.004 [-0.890-0.704] |
< -1.455, % (n) | 11.7 (26) | 12.8 (10) | 11.1 (16) |
≥ 0.676, % (n) | 25.2 (56) | 24.4 (19) | 25.7 (37) |
FibroTest® score | 0.187 [0.081–0.316] | 0.191 [0.105–0.280] | 0.180 [0.078–0.327] |
≤ 0.48, % (n) | 90.1 (219) | 93.3 (84) | 88.2 (135) |
> 0.58, % (n) | 6.2 (15) | 4.4 (4) | 7.2 (11) |
FNI | 0.394 ± 0.282 | 0.247 [0.119–0.471] | 0.444 [0.194–0.672]** |
< 0.10, % (n) | 18.5 (46) | 23.7 (22) | 15.4 (24) |
≥ 0.33, % (n) | 51.4 (128) | 38.7 (36) | 59.0 (92)** |
Inflammation score | |||
NashTest® score | 0.491 ± 0.182 | 0.440 ± 0.155 | 0.521 ± 0.190*** |
0.25, % (n) | 29.0 (70) | 34.1 (31) | 25.0 (39) |
0.75, % (n) | 25.3 (61) | 9.9 (9) | 33.3 (52)*** |