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Table 2 Associations between stress hyperglycemia ratio and clinical outcomes

From: Predictive value of the stress hyperglycemia ratio in dialysis patients with acute coronary syndrome: insights from a multi-center observational study

 

Model 1

   

Model 2

   

Model 3

  
 

HR

95% CI

P value

 

HR

95% CI

P value

 

HR

95% CI

P value

MACEa

           

SHR index

1.89

1.54–2.32

< 0.001

 

1.85

1.50–2.27

< 0.001

 

1.86

1.51–2.30

< 0.001

SHR1

1.09

0.82–1.44

0.562

 

1.09

0.83–1.45

0.531

 

1.07

0.81–1.42

0.634

SHR2

Reference

   

Reference

   

Reference

  

SHR3

1.98

1.53–2.56

< 0.001

 

1.94

1.50–2.51

< 0.001

 

1.92

1.48–2.49

< 0.001

All-cause Mortalityb

           

SHR index

2.31

1.87–2.87

< 0.001

 

2.25

1.81–2.79

< 0.001

 

2.20

1.76–2.77

< 0.001

SHR1

0.93

0.68–1.29

0.679

 

0.94

0.68–1.29

0.686

 

1.05

0.75–1.46

0.787

SHR2

Reference

   

Reference

   

Reference

  

SHR3

2.17

1.64–2.86

< 0.001

 

2.11

1.59–2.79

< 0.001

 

2.19

1.64–2.93

< 0.001

Cardiovascular Mortalityc

           

SHR index

2.55

2.00-3.25

< 0.001

 

2.49

1.95–3.18

< 0.001

 

2.48

1.92–3.20

< 0.001

SHR1

1.13

0.77–1.68

0.529

 

1.14

0.77–1.68

0.517

 

1.18

0.79–1.77

0.409

SHR2

Reference

   

Reference

   

Reference

  

SHR3

2.71

1.93–3.81

< 0.001

 

2.65

1.88–3.73

< 0.001

 

2.70

1.90–3.83

< 0.001

  1. Model 1: Unadjusted. Model 2: Adjusted for age and sex
  2. aModel 3 for MACE: Adjusted for age, sex, SBP, DBP, AMI as index presentation, GRACE score, left main disease, 3-vessel disease, moderate or severe calcification, dual antiplatelet therapy, ACE inhibitor or ARB, and calcium-channel blocker
  3. bModel 3 for all-cause mortality: Adjusted for age, sex, heart rate, SBP, DBP, diabetes mellitus, current smoker, AMI as index presentation, serum creatinine, GRACE score, left main disease, 3-vessel disease, moderate or severe calcification, PCI treatment, ACE inhibitor or ARB, and calcium-channel blocker
  4. cModel 3 for cardiovascular mortality: Adjusted for age, sex, SBP, DBP, dialysis vintage, AMI as index presentation, GRACE score, left main disease, 3-vessel disease, moderate or severe calcification, PCI treatment, ACE inhibitor or ARB, and calcium-channel blocker
  5. ACE = angiotensin-converting enzyme; AMI = acute myocardial infarction; ARB = angiotensin receptor blocker; CI = confidence interval; DBP = diastolic blood pressure; GRACE = Global Registry of Acute Coronary Events; HR = hazard ratio; MACE = Major Adverse Cardiovascular Events; PCI = percutaneous coronary intervention; SBP = systolic blood pressure; SHR = stress hyperglycemia ratio
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Cardiovascular Diabetology

ISSN: 1475-2840