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Table 1 Baseline demographic and clinical data of the study patients according to tertiles of stress hyperglycemia ratio

From: Predictive value of the stress hyperglycemia ratio in dialysis patients with acute coronary syndrome: insights from a multi-center observational study

Characteristic

Overall

N = 714

SHR1 (SHR ≤ 0.79)

N = 238

SHR2 (0.79 < SHR ≤ 1.10)

N = 238

SHR3 (SHR > 1.10)

N = 238

P value

Age, mean (SD), yrs

62.0 (10.4)

61.4 (11.2)

61.4 (9.5)

63.1 (10.4)

0.109

Male, No. (%)

535 (74.9)

181 (76.1)

179 (75.2)

175 (73.5)

0.812

SBP, mean (SD), mmHg

141.6 (24.9)

141.7 (24.2)

144.7 (24.0)

138.3 (26.1)

0.020

DBP, mean (SD), mmHg

78.3 (13.4)

77.7 (12.7)

79.9 (13.9)

77.3 (13.4)

0.066

Heart rate, mean (SD), beats/min

80.4 (15.0)

77.6 (14.7)

79.8 (12.4)

83.6 (17.1)

< 0.001

Medical history and risk factors, No. (%)

     

Hypertension

661 (92.6)

214 (89.9)

227 (95.4)

220 (92.4)

0.075

Diabetes mellitus

450 (63.0)

132 (55.5)

158 (66.4)

160 (67.2)

0.012

Current smoker

127 (17.8)

48 (20.2)

49 (20.6)

30 (12.6)

0.037

Atrial fibrillation

63 (8.8)

17 (7.1)

21 (8.8)

25 (10.5)

0.434

Cerebrovascular disease

139 (19.5)

39 (16.4)

45 (18.9)

55 (23.1)

0.174

Valvular disease

24 (3.4)

8 (3.4)

7 (2.9)

9 (3.8)

0.879

Peripheral arterial disease

74 (10.4)

22 (9.2)

25 (10.5)

27 (11.3)

0.751

Previous myocardial infarction

103 (14.4)

40 (16.8)

33 (13.9)

30 (12.6)

0.408

Previous intervention, No. (%)

     

PCI

144 (20.2)

58 (24.4)

44 (18.5)

42 (17.6)

0.138

CABG

12 (1.7)

5 (2.1)

4 (1.7)

3 (1.3)

0.775

Dialysis modality, No. (%)

    

0.010

Hemodialysis

655 (91.7)

225 (94.5)

222 (93.3)

208 (87.4)

 

Peritoneal dialysis

59 (8.3)

13 (5.5)

16 (6.7)

30 (12.6)

 

Vintage, yrs

    

0.163

<1

151 (21.1)

39 (16.4)

62 (26.1)

50 (21.0)

 

1–5

339 (47.5)

119 (50.0)

112 (47.1)

108 (45.4)

 

5–10

183 (25.6)

68 (28.6)

50 (21.0)

65 (27.3)

 

≥10

41 (5.7)

12 (5.0)

14 (5.9)

15 (6.3)

 

Cause of dialysis, No. (%)

    

0.022

Diabetes mellitus

267 (37.4)

73 (30.7)

98 (41.2)

96 (40.3)

 

Hypertension

87 (12.2)

39 (16.4)

25 (10.5)

23 (9.7)

 

Glomerulonephritis

168 (23.5)

67 (28.2)

54 (22.7)

47 (19.7)

 

Other/unknown

192 (26.9)

59 (24.8)

61 (25.6)

72 (30.3)

 

Index presentation, No. (%)

    

0.037

AMI

450 (63.0)

137 (57.6)

149 (62.6)

164 (68.9)

 

Unstable angina

264 (37.0)

101 (42.4)

89 (37.4)

74 (31.1)

 

Hemoglobin, g/L

105.7 (19.4)

105.2 (20.1)

108.2 (19.3)

103.7 (18.5)

0.038

ABG,

8.0 (4.4)

5.1 (1.8)

7.5 (2.6)

11.5 (5.2)

< 0.001

HbA1c, %

6.5 (1.7)

6.7 (1.7)

6.7 (1.7)

6.3 (1.9)

0.011

Serum creatinine, mg/dl

8.9 (3.2)

9.5 (3.3)

8.8 (2.9)

8.6 (3.3)

0.007

GRACE score

157.0 [133.0, 182.0]

150.5 [130.0, 173.0]

155.5 [133.0, 181.0]

161.0 [139.2, 188.0]

0.001

Procedure characteristic, No. (%)

     

Radial access

529 (74.1)

174 (73.1)

173 (72.7)

182 (76.5)

0.587

Extent of disease

     

Any left main disease

91 (12.7)

32 (13.4)

30 (12.6)

29 (12.2)

0.916

2-vessel disease

187 (26.2)

55 (23.1)

57 (23.9)

75 (31.5)

0.072

≥3-vessel disease

426 (59.7)

150 (63.0)

144 (60.5)

132 (55.5)

0.231

Moderate or severe calcification

324 (45.4)

115 (48.3)

100 (42.0)

109 (45.8)

0.381

PCI treatment

512 (71.7)

174 (73.1)

173 (72.7)

165 (69.3)

0.604

Discharge medications, No. (%)

     

Dual antiplatelet therapy

628 (88.0)

215 (90.3)

202 (84.9)

211 (88.7)

0.172

Aspirin

664 (93.0)

232 (97.5)

212 (89.1)

220 (92.4)

NA

Clopidogrel

596 (83.5)

200 (84.0)

195 (81.9)

201 (84.5)

NA

Ticagrelor

69 (9.7)

21 (8.8)

25 (10.5)

23 (9.7)

NA

ACE inhibitor or ARB

343 (48.0)

120 (50.4)

111 (46.6)

112 (47.1)

0.664

β-blocker

587 (82.2)

188 (79.0)

199 (83.6)

200 (84.0)

0.280

Calcium-channel blocker

467 (65.4)

161 (67.6)

163 (68.5)

143 (60.1)

0.105

Statin

678 (95.0)

228 (95.8)

223 (93.7)

227 (95.4)

0.541

  1. Data are presented as mean (SD) or n (%)
  2. ABG = admission blood glucose; ACE = angiotensin-converting enzyme; AMI = acute myocardial infarction; ARB = angiotensin receptor blocker; CABG = coronary artery bypass grafting; DBP = diastolic blood pressure; GRACE = Global Registry of Acute Coronary Events; PCI = percutaneous coronary intervention; SBP = systolic blood pressure; SHR = stress hyperglycemia ratio