Fig. 2
From: SGLT2 inhibition, circulating metabolites, and atrial fibrillation: a Mendelian randomization study
The forest plot of showing the effects of SGLT2 inhibition on circulating metabolites and the effects of metabolites on atrial fibrillation. (a) The effects of SGLT2 inhibition on the remaining 20 circulating metabolites selected from 168 metabolites, which were significantly associated with SGLT2 inhibition (Bonferroni-corrected P value threshold = 2.98 × 10− 4 [0.05/168]). (b) The effects of the above 20 metabolites on atrial fibrillation (Bonferroni-corrected P value threshold = 0.0025 [0.05/20]) CI, confidence interval; HDL, high-density lipoprotein; OR, odds ratio