Table 2 Baseline characteristics according to tertiles of the TyG index
|  | T1 TyG < 8.633 (n = 1509) | T2 TyG [8.633,9.096) (n = 1509) | T3 TyG ≥ 9.096 (n = 1512) | P value |
|---|---|---|---|---|
Age, years | 60.26 ± 10.10 | 59.78 ± 10.08 | 58.57 ± 9.80 | < 0.001 |
Male | 1215 (80.5) | 1169 (77.5) | 1141 (75.5) | 0.003 |
BMI, kg/m2 | 25.07 ± 3.12 | 26.04 ± 3.13 | 26.55 ± 3.10 | < 0.001 |
DM | 358 (23.7) | 611 (40.5) | 982 (64.9) | < 0.001 |
Hypertension | 858 (56.9) | 971 (64.3) | 1037 (68.6) | < 0.001 |
SBP, mmHg | 129.64 ± 17.78 | 130.99 ± 17.54 | 130.95 ± 17.64 | 0.058 |
DBP, mmHg | 76.54 ± 10.71 | 77.43 ± 11.01 | 77.87 ± 11.04 | 0.003 |
Current smoker | 467 (30.9) | 471 (31.2) | 509 (33.7) | 0.210 |
ACS | 904 (59.9) | 965 (63.9) | 944 (62.4) | 0.069 |
Family history of CAD | 176 (11.7) | 184 (12.2) | 202 (13.4) | 0.351 |
Previous MI | 335 (22.2) | 354 (23.5) | 346 (22.9) | 0.712 |
Previous PCI | 290 (19.2) | 284 (18.8) | 322 (21.3) | 0.186 |
Previous CABG | 20 (1.3) | 18 (1.2) | 14 (0.9) | 0.576 |
Previous stroke | 201 (13.3) | 173 (11.5) | 208 (13.8) | 0.136 |
Previous PAD | 103 (6.8) | 77 (5.1) | 80 (5.3) | 0.083 |
CKD | 18 (1.2) | 29 (1.9) | 43 (2.8) | 0.005 |
LVEF, % | 62.68 ± 4.90 | 62.41 ± 5.44 | 62.59 ± 4.97 | 0.338 |
Laboratory results | Â | Â | Â | Â |
TyG | 8.30 ± 0.25 | 8.86 ± 0.14 | 9.53 ± 0.36 | < 0.001 |
FBG, mmol/L | 5.34 ± 0.95 | 6.07 ± 1.43 | 7.96 ± 3.09 | < 0.001 |
HbA1c, % | 5.96 ± 0.80 | 6.28 ± 0.97 | 7.03 ± 1.48 | < 0.001 |
TC, mmol/L | 3.68 ± 0.92 | 4.02 ± 0.98 | 4.32 ± 1.08 | < 0.001 |
TG, mmol/L | 0.99 ± 0.24 | 1.53 ± 0.34 | 2.45 ± 0.86 | < 0.001 |
LDL-C, mmol/L | 2.18 ± 0.80 | 2.48 ± 0.86 | 2.58 ± 0.94 | < 0.001 |
HDL-C, mmol/L | 1.21 ± 0.33 | 1.10 ± 0.28 | 1.01 ± 0.25 | < 0.001 |
hsCRP, mg/L | 2.32 ± 2.95 | 2.79 ± 3.21 | 2.89 ± 3.01 | < 0.001 |
Creatinine, µmol/L | 81.00 ± 15.77 | 83.04 ± 17.20 | 84.70 ± 28.13 | < 0.001 |
Lipoprotein(a), mg/L | 32.49 ± 31.10 | 30.35 ± 30.34 | 28.42 ± 30.37 | 0.001 |
Medications | Â | Â | Â | Â |
Clopidogrel | 1298 (86.0) | 1277 (84.6) | 1285 (85.0) | 0.536 |
ACEI/ARB | 371 (24.6) | 385 (25.5) | 414 (27.4) | 0.202 |
β-blocker | 1288 (85.4) | 1340 (88.8) | 1366 (90.3) | < 0.001 |
CCB | 511 (33.9) | 547 (36.2) | 576 (38.1) | 0.052 |
Statins | 1457 (96.6) | 1456 (96.5) | 1470 (97.2) | 0.452 |
Antidiabetic drugs | 308 (20.4) | 460 (30.5) | 746 (49.3) | < 0.001 |
Nitrate | 1457 (96.6) | 1459 (96.7) | 1475 (97.6) | 0.224 |
Angiographic findings | Â | Â | Â | Â |
SYNTAX score | 15.29 ± 5.58 | 15.55 ± 5.78 | 15.74 ± 5.92 | 0.078 |
Left main disease | 165 (10.9) | 183 (12.1) | 184 (12.2) | 0.489 |
three-vessel disease | 585 (38.8) | 608 (40.3) | 677 (44.8) | 0.002 |
Chronic total occlusion | 123 (8.2) | 125 (8.3) | 144 (9.5) | 0.334 |
Type B2/C lesion | 1269 (84.1) | 1259 (83.4) | 1283 (84.9) | 0.564 |
Ostial lesions | 363 (24.1) | 357 (23.7) | 340 (22.5) | 0.571 |
Thrombotic lesions | 15 (1.0) | 18 (1.2) | 26 (1.7) | 0.192 |
Severe calcification | 60 (4.0) | 44 (2.9) | 49 (3.2) | 0.255 |