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Table 7 Association between the NT-proBNP and the risk of carotid artery plaques according to different glucose regulation state and age

From: Relationship between the circulating N-terminal pro B-type natriuretic peptide and the risk of carotid artery plaque in different glucose metabolic states in patients with coronary heart disease: a CSCD-TCM plus study in China

Variables

Carotid artery plaques

OR (95% CI)a

P-value

OR (95% CI)b

P-value

OR (95% CI)c

P-value

≤ 60

 Normal glucose regulation

  Continuous

(per 1 SD increase)

1.42(1.08–1.86)

0.012

1.34(1.03–1.75)

0.030

3.00(0.91–9.90)

0.072

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.11(0.74–1.65)

0.621

1.08(0.72–1.62)

0.727

0.84(0.50–1.40)

0.493

  > 480

1.76(1.10–2.83)

0.020

1.54(0.95–2.51)

0.082

1.68(0.87–3.50)

0.163

  Ptrend

0.021

 

0.082

 

0.097

 

 Prediabetes

  Continuous

(per 1 SD increase)

0.95(0.77–1.17)

0.637

0.94(0.77–1.16)

0.581

0.75(0.50–1.12)

0.162

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.71(0.98–2.96)

0.058

1.81(1.02–3.20)

0.043

1.57(1.78–3.17)

0.206

  > 480

1.79(1.04–3.11)

0.037

1.62(0.92–2.86)

0.095

0.89(0.36–2.21)

0.807

  Ptrend

0.093

 

0.224

 

0.594

 

 Diabetes

  Continuous

(per 1 SD increase)

3.41(1.30–8.93)

0.013

3.27(1.26–8.53)

0.015

1.51(0.55–4.15)

0.420

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.66(1.02–2.68)

0.041

1.55(0.95–2.53)

0.078

1.50(0.82–2.76)

0.189

  > 480

2.23(1.38–3.60)

0.001

2.18(1.34–3.54)

0.002

1.47(0.73–2.94)

0.282

  Ptrend

0.005

 

0.005

 

0.438

 

> 60

 Normal glucose regulation

  Continuous

(per 1 SD increase)

2.71(1.79–7.74)

 < 0.001

3.12(1.51–6.44)

0.002

1.94(0.76–4.96)

0.166

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.16(0.80–1.67)

0.432

1.23(0.85–1.78)

0.280

1.05(0.66–1.68)

0.832

  > 480

1.94(1.30–2.90)

0.001

1.85(1.23–2.78)

0.003

1.43(0.82–2.47)

0.208

  Ptrend

0.001

 

0.005

 

0.179

 

 Prediabetes

  Continuous

(per 1 SD increase)

1.61(0.97–2.68)

0.066

1.45(0.91–2.30)

0.121

7.06(1.95–25.81)

0.002

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.24(0.80–1.93)

0.342

1.23(0.79–1.93)

0.359

1.24(0.72–2.15)

0.443

 > 480

2.33(1.40–3.87)

0.001

2.08(1.25–3.48)

0.005

3.44(1.53–7.76)

0.002

Ptrend

0.001

 

0.007

 

0.003

 

 Diabetes

  Continuous

(per 1 SD increase)

1.15(0.76–1.75)

0.501

1.18(0.86–1.63)

0.304

1.27(0.74–2.17)

0.383

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.01(0.65–1.56)

0.979

1.05(0.67–1.63)

0.829

0.94(0.56–1.61)

0.824

  > 480

1.74(1.07–2.81)

0.025

1.75(1.08–2.83)

0.023

2.32(1.15–4.65)

0.018

  Ptrend

0.009

 

0.012

 

0.005

 
  1. aModel 1: unadjusted
  2. bModel 2: adjusted for sex
  3. cModel 3: adjusted for sex, smoking, drinking, hypertension, diabetes, hyperlipidemia, LVEF, proteinuria, previous MI, PCI or CABG, use of antihypertensives, and use of antilipidemic