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Table 6 Association between the NT-proBNP and the risk of carotid artery plaques according to different glucose regulation state and sex

From: Relationship between the circulating N-terminal pro B-type natriuretic peptide and the risk of carotid artery plaque in different glucose metabolic states in patients with coronary heart disease: a CSCD-TCM plus study in China

Variables

Carotid artery plaques

OR (95% CI)a

P-value

OR (95% CI)b

P-value

OR (95% CI)c

P-value

Male

 Normal glucose regulation

  Continuous

(per 1 SD increase)

1.99(1.22–3.24)

0.006

1.74(1.08–2.80)

0.023

1.56(0.78–3.15)

0.212

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.37(0.90–2.08)

0.144

0.93(0.59–1.47)

0.742

1.05(0.61–1.81)

0.862

  > 480

2.06(1.33–3.21)

0.001

1.35(0.82–2.20)

0.224

1.11(0.60–2.04)

0.737

  Ptrend

0.004

 

0.131

 

0.767

 

 Prediabetes

  Continuous

(per 1 SD increase)

0.98(0.8–1.21)

0.864

0.83(0.67–1.03)

0.090

0.95(0.63–1.41)

0.792

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.93(1.13–3.31)

0.017

1.26(0.71–2.23)

0.430

1.35(0.68–2.71)

0.392

  > 480

2.49(2.47–3.21)

0.001

1.47(0.84–2.58)

0.182

3.32(1.27–8.69)

0.015

  Ptrend

0.007

 

0.255

 

0.020

 

 Diabetes

  Continuous

(per 1 SD increase)

1.26(0.86–1.83)

0.237

1.16(0.82–1.64)

0.409

1.16(0.68–1.98)

0.588

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.41(0.88–2.24)

0.153

1.22(0.76–2.00)

0.421

1.10(0.62–1.95)

0.734

  > 480

1.98(2.24–3.16)

0.004

1.65(1.02–2.67)

0.043

2.05(1.99–4.28)

0.054

  Ptrend

0.012

 

0.061

 

0.050

 

Female

 Normal glucose regulation

  Continuous

(per 1 SD increase)

4.429(1.92–9.96)

 < 0.001

2.60(1.29–4.27)

0.008

1.68(0.57–4.93)

0.343

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.49(1.07–2.07)

0.018

1.04(0.73–1.49)

0.816

0.80(0.50–1.26)

0.336

  > 480

2.64(1.77–3.94)

 < 0.001

1.50(0.97–2.32)

0.068

1.03(0.57–1.88)

0.925

  Ptrend

 < 0.001

 

0.053

 

0.621

 

 Prediabetes

Continuous

(per 1 SD increase)

2.01(1.04–3.89)

0.038

1.79(0.98–3.25)

0.056

1.46(0.73–2.92)

0.288

 < 56

Reference

 

Reference

 

Reference

 

[56–480]

1.92(1.27–2.90)

0.002

1.25(0.80–1.97)

0.335

1.23(0.70–2.14)

0.474

 > 480

2.62(1.61–4.26)

 < 0.001

1.51(0.87–2.56)

0.130

1.48(0.71–3.07)

0.293

Ptrend

0.002

 

0.197

 

0.366

 

 Diabetes

  Continuous

(per 1 SD increase)

2.71(1.29–5.71)

0.009

2.00(1.03–3.90)

0.042

1.68(0.63–4.45)

0.297

  < 56

Reference

 

Reference

 

Reference

 

  [56–480]

1.79(1.19–2.70)

0.005

1.01(0.64–1.58)

0.979

0.95(0.55–1.66)

0.859

  > 480

2.76(1.74–4.38)

 < 0.001

1.62(0.99–2.66)

0.056

1.60(0.81–3.15)

0.175

  Ptrend

 < 0.001

 

0.033

 

0.109

 
  1. aModel 1: unadjusted
  2. bModel 2: adjusted for age
  3. cModel 3: adjusted for age, smoking, drinking, hypertension, diabetes, hyperlipidemia, LVEF, proteinuria, previous MI, PCI or CABG, use of antihypertensives, and use of antilipidemic