Table 1 Baseline clinical characteristics according to NT-proBNP
Characteristics | Total | T1 N = 1687 | T2 N = 1710 | T3 N = 1696 | P-value |
|---|---|---|---|---|---|
Age |  < 0.001 | ||||
 Total | 65(60,71) | 62(56,67) | 66(61,70) | 67(61,71) |  |
  ≤ 60 | 1461(28.7) | 700(41.5) | 390(22.8) | 371(21.9) |  |
 > 60 | 3632(71.3) | 987(58.5) | 1320(77.2) | 1325(78.1) |  |
Sex |  < 0.001 | ||||
 Male | 2597(51.0) | 867(51.4) | 775(45.2) | 955(56.3) |  |
 Female | 2490(49.0) | 820(48.6) | 935(54.7) | 741(43.7) |  |
SBP (mmHg) | 140.0(130.0,160.0) | 140.0(130.0,160.0) | 143.0(130.0,160.0) | 140.0(127.0,160.0) | 0.061 |
DBP (mmHg) | 81.0(80.0,90.0) | 85.0(80.0,93.0) | 80.0(80.0,90.0) | 80.0(76.0,90.0) |  < 0.001 |
Drinking (%) | 1242(24.4) | 459(27.2) | 398(23.3) | 385(22.7) | 0.004 |
Smoking (%) | 2105(41.3) | 728(43.2) | 687(40.2) | 690(40.7) | 0.170 |
Hypertension (%) | 3915(76.9) | 1336(79.2) | 1372(80.2) | 1207(71.2) |  < 0.001 |
Hyperlipidemia (%) | 902(17.7) | 402(23.8) | 324(18.9) | 176(10.4) |  < 0.001 |
HbA1c (%) | 6.1(5.6,7.1) | 6.0(5.5,6.9) | 6.1(5.6,7.1) | 6.3(5.6,7.5) |  < 0.001 |
FBG (mmol/l) | 6.2(5.2,8.3) | 6.3(5.3,8.3) | 6.2(5.2,8.1) | 6.4(5.2,8.7) | 0.019 |
CRP (mg/l) | 3.5(2.0,7.4) | 2.6(1.5,4.3) | 2.8(1.8,4.9) | 6.0(2.9,15.4) |  < 0.001 |
eGFR (ml/min/1.73m2) | 109.8(88.3,131.1) | 110.1(91.8,129.0) | 110.2(84.2,126.9) | 108.5(83.0,130.2) | 0.831 |
LVEF (%) | 61.0(56.8,65.0) | 63.0(60.0,66.0) | 62.0(59.0,65.0) | 58.0(51.0,62.0) |  < 0.001 |
TG (mmol/l) | 1.4(1.0,2.1) | 1.5(1.1,2.1) | 1.4(1.0,2.0) | 1.2(0.9,1.7) |  < 0.001 |
TC (mmol/l) | 4.3(3.6,5.1) | 4.5(3.8,5.2) | 4.5(3.7,5.2) | 4.0(3.3,4.9) |  < 0.001 |
LDL-C (mmol/l) | 2.8(2.2,3.5) | 3.0(2.4,3.6) | 2.9(2.3,3.6) | 2.6(2.0,3.4) |  < 0.001 |
HDL-C (mmol/l) | 0.9(1.0,1.3) | 1.0(0.9,1.3) | 1.1(0.9,1.3) | 1.0(0.8,1.2) |  < 0.001 |
Proteinuria (%) | 283(5.6) | 25(1.5) | 65(3.8) | 193(11.4) |  < 0.001 |
NYHA classification (%) |  < 0.001 | ||||
 I | 558(11.0) | 288(17.1) | 190(11.1) | 80(4.7) |  |
 II | 3049(59.9) | 1180(69.9) | 1181(69.1) | 688(40.6) |  |
 III | 1201(23.6) | 197(11.7) | 298(17.4) | 706(41.6) |  |
 IV | 285(5.6) | 22(1.3) | 41(2.4) | 222(13.1) |  |
Previous PCI (%) | 462(9.1) | 129(7.6) | 159(9.3) | 174(10.3) | 0.028 |
Previous CABG (%) | 123(2.4) | 20(1.2) | 38(2.2) | 65(3.8) |  < 0.001 |
Previous MI (%) | 616(12.1) | 112(6.6) | 173(10.1) | 331(19.5) |  < 0.001 |
Glucose regulation state (%) | 0.021 | ||||
 NG | 1807(35.5) | 583(34.6) | 647(37.8) | 577(34.0) |  |
 Pre-DM | 1325(26.0) | 472(28.0) | 427(25.0) | 426(25.1) |  |
 DM | 1961(38.5) | 632(37.5) | 636(37.2) | 693(40.9) |  |
Current antihypertensive medication (%) | 3126(61.4) | 1012(60.0) | 1069(62.5) | 1045(61.6) | 0.309 |
Current antilipidemic medication (%) | 3808(74.8) | 1282(76.0) | 1305(76.3) | 1221(72.0) | 0.005 |
CIMT (cm) | 0.9(0.8,1.1) | 0.9(0.8,1.0) | 0.9(0.8,1.1) | 1.0(0.9,1.1) |  < 0.001 |
Carotid artery plaque (%) | 4177(82.0) | 1270(75.3) | 1408(82.3) | 1499(88.4) |  < 0.001 |
Number of carotid artery plaque (%) |  < 0.001 | ||||
 0 | 916(18.0) | 417(24.7) | 302(17.7) | 197(11.6) |  |
 1 | 399(7.8) | 160(9.5) | 146(8.5) | 93(5.5) |  |
  ≥ 2 | 3778(74.2) | 1110(65.8) | 1262(73.8) | 1406(82.9) |  |
Carotid artery plaque echo property (%) |  < 0.001 | ||||
 Hypoechoic plaque | 192(3.8) | 86(5.1) | 49(2.9) | 57(3.4) |  |
 Isoechoic plaque | 379(7.4) | 148(8.8) | 128(7.5) | 103(6.1) |  |
 Hyperechoic plaque | 2413(47.4) | 691(41.0) | 809(47.3) | 913(53.8) |  |
 Mixture plaque | 1200(23.6) | 348(20.6) | 423(24.7) | 429(25.3) |  |