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Table 1 Comparison of baseline characteristics between groups stratified by quartile of SHR

From: Impact of stress hyperglycemia ratio on mortality in patients with critical acute myocardial infarction: insight from american MIMIC-IV and the chinese CIN-II study

Characteristics

Overall

Quartile 1

Quartile 2

Quartile 3

Quartile 4

P

value

Overall

Quartile 1

Quartile 2

Quartile 3

Quartile 4

P

value

(MIMIC-IV)

< 0.88

0.88–1.04

1.04–1.30

≥ 1.30

(CIN-II)

< 0.86

0.86–1.02

1.02–1.23

≥ 1.23

 N = 2166

 N = 542

 N = 542

 N = 540

 N = 542

 N = 2171

 N = 543

 N = 543

 N = 542

 N = 543

SHR

1.16 (0.56)

0.75 (0.12)

0.96 (0.05)

1.15 (0.07)

1.77 (0.81)

< 0.001

1.08 (0.34)

0.73 (0.10)

0.94 (0.05)

1.12 (0.06)

1.53 (0.31)

< 0.001

Age, years

69.0 (12.3)

69.2 (12.2)

69.1 (12.5)

68.1 (12.8)

69.6 (11.8)

0.191

62.9 (12.1)

62.7 (11.8)

62.2 (12.0)

62.3 (12.6)

64.2 (12.0)

0.018

Female

665 (30.7)

167 (30.8)

158 (29.2)

154 (28.5)

186 (34.3)

0.161

447 (20.6)

105 (19.3)

101 (18.6)

120 (22.1)

121 (22.3)

0.310

Medical history

            

STEMI

604 (27.9)

96 (17.7)

153 (28.2)

166 (30.7)

189 (34.9)

< 0.001

1556 (71.7)

353 (65.0)

412 (75.9)

394 (72.7)

397 (73.1)

< 0.001

NSTEMI

1443 (66.6)

425 (78.4)

364 (67.2)

344 (63.7)

310 (57.2)

< 0.001

362 (16.7)

99 (18.2)

76 (14.0)

88 (16.2)

99 (18.2)

0.189

Hypertension

1435 (66.3)

364 (67.2)

346 (63.8)

372 (68.9)

353 (65.1)

0.308

1088 (50.1)

270 (49.7)

253 (46.6)

277 (51.1)

288 (53.0)

0.187

Congestive heart failure

966 (44.6)

190 (35.1)

212 (39.1)

250 (46.3)

314 (57.9)

< 0.001

923 (42.5)

230 (42.4)

204 (37.6)

230 (42.4)

259 (47.7)

0.010

Diabetes mellitus

956 (44.1)

260 (48.0)

187 (34.5)

211 (39.1)

298 (55.0)

< 0.001

915 (42.1)

256 (47.1)

187 (34.4)

201 (37.1)

271 (49.9)

< 0.001

Chronic kidney disease

790 (36.5)

180 (33.2)

163 (30.1)

186 (34.4)

261 (48.2)

< 0.001

710 (32.7)

169 (31.1)

147 (27.1)

166 (30.6)

228 (42.0)

< 0.001

Atrial fibrillation

753 (34.8)

203 (37.5)

166 (30.6)

171 (31.7)

213 (39.3)

0.005

147 (6.8)

36 (6.6)

31 (5.7)

41 (7.6)

39 (7.2)

0.643

Stroke

365 (16.9)

82 (15.1)

92 (17.0)

83 (15.4)

108 (19.9)

0.130

166 (7.6)

44 (8.1)

39 (7.2)

33 (6.1)

50 (9.2)

0.255

Anemia

1223 (56.5)

297 (54.8)

290 (53.5)

309 (57.2)

327 (60.3)

0.113

885 (42.0)

217 (41.5)

217 (41.1)

213 (40.5)

238 (44.7)

0.502

qSOFA score ≥ 2

152 (7.0)

36 (6.6)

28 (5.2)

43 (8.0)

45 (8.3)

0.166

187 (20.8)

44 (18.8)

44 (20.2)

40 (19.7)

59 (24.1)

0.500

Procedure information

            

PCI therapy

295 (13.6)

53 (9.8)

93 (17.2)

81 (15.0)

68 (12.5)

0.003

1938 (89.3)

460 (84.7)

495 (91.2)

496 (91.5)

487 (89.7)

< 0.001

CABG

492 (22.7)

165 (30.4)

136 (25.1)

114 (21.1)

77 (14.2)

< 0.001

22 (1.0)

5 (0.9)

7 (1.3)

5 (0.9)

5 (0.9)

0.908

RRT

63 (2.9)

10 (1.8)

10 (1.8)

18 (3.3)

25 (4.6)

0.017

146 (6.7)

31 (5.7)

29 (5.3)

28 (5.2)

58 (10.7)

< 0.001

Laboratory indexes

            

Leukocyte, 10^9/L

10.9 (7.3)

9.5 (7.9)

10.1 (4.2)

11.3 (9.4)

12.7 (6.1)

< 0.001

11.3 (4.3)

10.1 (3.8)

11.1 (3.9)

11.7 (4.4)

12.4 (4.8)

< 0.001

Lymphocyte, 10^9/L

2.0 (5.2)

2.7 (10.0)

1.9 (1.1)

1.8 (2.2)

1.5 (1.0)

0.018

1.6 (0.7)

1.8 (0.7)

1.6 (0.7)

1.5 (0.7)

1.4 (0.7)

< 0.001

Neutrophile, 10^9/L

10.2 (5.5)

8.8 (4.5)

10.0 (5.0)

10.2 (6.0)

11.5 (5.9)

< 0.001

9.0 (4.0)

7.4 (3.3)

8.7 (3.5)

9.5 (4.0)

10.3 (4.4)

< 0.001

Hemoglobin, g/L

122.1 (21.6)

122.8 (20.2)

124.1 (20.9)

122.3 (21.3)

119.0 (23.5)

0.001

130.0 (20.6)

129.6 (19.4)

131.2 (19.7)

130.9 (20.6)

128.5 (22.5)

0.132

LDLC, mmol/L

5.2 (2.4)

5.3 (2.2)

5.2 (2.3)

5.3 (2.1)

5.1 (3.0)

0.894

3.1 (1.0)

3.1 (1.0)

3.1 (1.0)

3.1 (1.1)

3.0 (1.0)

0.295

HDLC, mmol/L

2.5 (0.9)

2.4 (0.8)

2.5 (0.9)

2.4 (0.8)

2.6 (1.0)

0.153

1.0 (0.3)

1.0 (0.3)

1.0 (0.3)

1.0 (0.3)

1.0 (0.3)

0.030

SCr. mg/dL

1.4 (1.4)

1.3 (1.3)

1.4 (1.4)

1.4 (1.2)

1.6 (1.6)

0.000

1.3 (1.1)

1.3 (1.2)

1.2 (1.0)

1.2 (1.0)

1.5 (1.3)

< 0.001

FPG, mmol/L

8.9 (5.1)

6.2 (1.8)

7.2 (2.2)

8.6 (3.0)

13.8 (7.1)

< 0.001

8.5 (3.6)

6.0 (1.7)

7.2 (2.1)

8.7 (2.8)

12.2 (4.1)

< 0.001

HbA1c, %

6.5 (1.6)

6.9 (1.8)

6.3 (1.4)

6.3 (1.6)

6.6 (1.6)

< 0.001

6.6 (1.5)

6.9 (1.6)

6.5 (1.4)

6.5 (1.5)

6.6 (1.5)

< 0.001

Medication

            

ACEI/ARB

1265 (58.4)

308 (56.8)

338 (62.4)

319 (59.1)

300 (55.4)

0.101

1383 (71.2)

341 (69.3)

362 (72.0)

358 (72.5)

322 (70.9)

0.704

β-Blocker

2056 (94.9)

526 (97.0)

527 (97.2)

512 (94.8)

491 (90.6)

< 0.001

1582 (81.4)

386 (78.5)

413 (82.1)

400 (81.0)

383 (84.4)

0.128

Statins

2036 (94.0)

515 (95.0)

521 (96.1)

500 (92.6)

500 (92.3)

0.017

1764 (90.8)

441 (89.6)

459 (91.3)

449 (90.9)

415 (91.4)

0.770

Aspirin

2094 (96.7)

534 (98.5)

536 (98.9)

513 (95.0)

511 (94.3)

< 0.001

1805 (92.9)

450 (91.5)

468 (93.0)

468 (94.7)

419 (92.3)

0.227

Diuretic

1661 (76.7)

443 (81.7)

396 (73.1)

408 (75.6)

414 (76.4)

0.007

466 (24.0)

113 (23.0)

104 (20.7)

112 (22.7)

137 (30.2)

0.004

OAD

            

Insulin

1719 (79.4)

468 (86.3)

402 (74.2)

400 (74.1)

449 (82.8)

< 0.001

64 (3.3)

20 (4.1)

14 (2.8)

14 (2.8)

16 (3.5)

0.629

  1. Data are means ± SD, median (interquartile range), or n (%)
  2. ACEI/ARB = angiotensin converting enzyme inhibitor or angiotensin receptor blocker, CABG: coronary artery bypass grafting, HbA1c = glycated hemoglobin, HDLC = high density lipoprotein cholesterol, LDLC = low density lipoprotein cholesterol, SCr = Serum Creatinine. qSOFA = quick sequential organ failure assessment, PCI = percutaneous coronary intervention, SHR = stress hyperglycemia ratio, RRT = renal replacement therapy
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Cardiovascular Diabetology

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