Fig. 3
Spline curves showing Log HRs and 95%CIs (shaded) for CVD among individuals without diabetes
Knots were placed at the 5th, 25th, 50th, 75th, and 95th percentiles of the eGFR slope.
The model was adjusted for the following variables (set at representative levels): sex (female), age (45 years), BMI (27.7 kg/m2), smoking status (never), hypertension (no), hypercholesterolemia (no), FH-CVD (no), marital status (married), education level (6–12 years), FPG (93 mg/dl), eGFR at index date (78.8), RAAS-I drugs = no. HR: hazard ratio; eGFR: estimated glomerular filtration rate; CI: confidence interval; BMI: body mass index; FH-CVD: family history of CVD; FPG: fasting blood glucose; RAAS-I: renin-angiotensin-aldosterone system inhibitors