Table 3 Multivariate Cox regression analysis for incident MACE, coronary and cerebrovascular events, and overall mortality

All

 Uric acid, mg/dl

1.415

1.328–1.508

0.000

1.493

1.375–1.621

0.000

1.256

1.109–1.423

0.000

1.469

1.237–1.745

0.000

 HOMA, 1 unit

1.402

1.274–1.542

0.000

1.401

1.239–1.585

0.000

1.469

1.232–1.751

0.000

–

–

–

 hs-CRP, mg/L

1.302

1.177–1.441

0.000

1.293

1.132–1476

0.000

1.294

1.066–1.571

0.009

1.324

1.010–1.735

0.042

 Systolic BP, 10 mmHg

1.085

1.004–1.172

0.040

1.167

1.057–1.288

0.002

–

–

–

–

–

–

 Age, 10 yrs

1.010

1.002–1.019

0.020

1.015

1.004–1.027

0.007

–

–

–

–

–

–

 e-GFR, 10 ml/min/1.7m²

–

–

–

–

–

–

–

–

–

0.855

0.755–0.968

0.013

Males

 Uric acid, mg/dl

1.372

1.240–1.519

0.000

1.435

1.261–1.633

0.000

1.183

1.086–1.282

0.18

1.388

1.270–1.613

0.000

 hs-CRP, mg/L

1.277

1.101–1.480

0.001

–

–

–

1.473

1.082–2.005

0.014

–

–

–

 HOMA, 1 unit

1.216

1.029–1.438

0.022

1.270

1.023–1.576

0.030

–

–

–

–

–

–

 Systolic BP, 10 mmHg

–

–

–

1.292

1.113–1.500

0.000

–

–

–

–

–

–

 Age, 10 years

–

–

–

1.017

1.000–1.034

0.050

–

–

–

–

–

–

 Heart rate, 10 beats/min

1.419

1.062–1.896

0.018

 e-GFR, 10 ml/min/1.7m²

–

–

–

–

–

–

–

–

–

0.685

0.572–0.821

0.000

Females

 HOMA, 1 unit

1.526

1.356–1.517

0.000

1.510

1.294–1.763

0.000

1.554

1.270–1.901

0.000

–

–

–

 Uric acid, 1 mg/dl

1.431

1.318–1.553

0.000

1.509

1.360–1.676

0.000

1.273

1.093–1.482

0.002

1.416

1.113–1.800

0.005

 hs-CRP, 1 mg/L

1.367

1.182–1.580

0.000

1.401

1.166–1.683

0.000

–

–

–

–

–

–

 e-GFR, 10 ml/min/1.7m²

0.915

0.854–0.981

0.012

–

–

–

–

–

–

0.634

0.470–0.854

0.003

 Age, 10 years

–

–

–

1.018

1.002–1.033

0.026

–

–

–

–

–

–