Table 2 Univariate Cox regression analysis for incident MACE, coronary and cerebrovascular events, and overall mortality

All

 HOMA, 1 unit

1.358–1.626

1.347–1.700

1.272–1.777

1.016–1.725

 Uric acid, mg/dl

1.349–1.521

1.387–1.619

1.148–1.458

1.216–1.684

 Sex, females

1.063–1.559

1.044–1.723

1.002–2.086

0.498–1.429

 hs-CRP, mg/L

1.158–1.422

1.108–1.451

1.049–1.552

1.039–1.786

 SBP, 10 mmHg

1.056–1.228

1.15–1.350

0.885–1.191

.0795–1.232

 Age, 10 yrs

1.002–1.019

1.005–1.028

0.989–1.021

0.972–1.017

 e-GFR, 10 ml/min/1.7m²

0.882–0.962

0.871–0.975

0.893–1.049

0.725–0.934

 Smoking, yes/no

0.968–1.452

0.912–1.534

0.947–1.991

0.498–1.589

 Total cholesterol, 10 mg/dl

0.996–1001

0.946–1.018

0.912–1.016

0.877–1.077

 LDL-cholesterol, 10 mg/dl

0.999–1004

0.980–1.049

0.944–1.044

1.008–1.156

 Triglyceride, 10 mg/dl

0.997–1.004

0.950–1.040

0.973–1.105

0.914–1.123

 Body mass index, Kg/m²

0.953–1.008

0.967–1.040

0.898–1.007

0.851–1.097

 Heart rate, 10 beats/min

0.997–1.018

0.940–1.230

0.940–1.384

0.777–1.369

Males

 Uric acid, mg/dl

1.259–1.531

1.275–1.641

1.098–1.477

1.165–1.876

 hs-CRP, mg/L

1.142–1.536

1.054–1.566

1.028–1.833

0.978–1.965

 HOMA, 1 unit

1.091–1.527

1.104–1.713

0.845–1.637

0.784–1.817

 SBP, 10 mmHg

1.026–1.290

1.151–1.533

0.799–1.285

0.544–1.078

 Age, 10 yrs

0.995–1.020

1.002–1.035

0.973–1.021

0.955–1.015

 Smoking

0.908–1.614

0.754–1.677

1.078–3.325

0.438–2.071

 e-GFR, 10 ml/min/1.7m²

0.918–1.058

0.913–1.102

0.925–1.230

0.687–0.977

 Total cholesterol, 10 mg/dl

0.924–1.009

0.907–1.019

0.874–1.040

0.903–1.115

 LDL-cholesterol, 10 mg/dl

0.967–1.082

0.943–1.049

0.895–1.051

1.007–1.212

 Triglyceride, 10 mg/dl

0.975–1082

0.941–1.080

0.931–1.242

0.795–1.051

 Body mass index, Kg/m²

0.930–1.017

0.952–1.068

0.860–1.207

0.798–1008

 Heart rate, 10 beats/min

0.963–1.301

0.817–1.216

1.008–1.311

0.796–1.679

Females

 HOMA, 1 unit

1.395–1.727

1.342–1.770

1.319–1.936

1.048–2.091

 Uric acid, 1 mg/dl

1.341–1.567

1.373–1.675

1.140–1.535

1.130–1.803

 hs-CRP, 1 mg/L

1.056–1.415

1.010–1.475

0.885–1.526

0.914–2.176

 SBP, 10 mmHg

1.000–1.224

0.992–1.284

0.831–1.221

0.937–1.700

 Age, 10 yrs

1.003–1.026

1.002–1.032

0.992–1.035

0.972–1.042

 e-GFR, 10 ml/min/1.7m²

0.822–0.950

0.806–0.971

0.853–1.093

0.464–0.840

 Smoking, yes/no

0.861–1.475

0.853–1.698

0.875–1.325

0.351–2.016

 Total cholesterol, 10 mg/dl

0.957–1.030

0.949–1.044

0.904–1.037

0.936–1.069

 LDL-cholesterol, 10 mg/dl

0.988–1.058

0.980–1.071

0.943–1.071

0.952–1.170

 Triglyceride, 10 mg/dl

0.944–1.036

0.929–1.047

0.890–1.060

0.918–1.196

 Body mass index, Kg/m²

0.950–1.022

0.960–1.052

0.897–1.028

0.843–1.055

 Heart rate, 10 beats/min

0.922–1.225

0.964–1.389

0.956–1.491

0.560–1.346