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Table 2 Association between Hs-cTn concentration and all-cause and cardiovascular mortality

From: Association between high sensitivity cardiac troponin and mortality risk in the non-diabetic population: findings from the National Health and Nutrition Examination Survey

 

Hazard ratio (95% confidence interval)

P-trend

< LOD

LOD–99th URL

≥ 99th URL

All-cause mortality

 Hs-cTnI

  Model 1

Ref

1.17 (1.02, 1.34)

1.98 (1.57, 2.50)

< 0.001

  Model 2

Ref

1.08 (0.94, 1.25)

1.74 (1.35, 2.24)

< 0.001

 Hs-cTnT

  Model 1

Ref

1.09 (0.83, 1.42)

2.37 (1.77, 3.15)

< 0.001

  Model 2

Ref

1.07 (0.81, 1.41)

2.07 (1.53, 2.81)

< 0.001

Cardiovascular mortality

 Hs-cTnI

  Model 1

Ref

1.24 (0.94, 1.64)

2.92 (1.98, 4.32)

< 0.001

  Model 2

Ref

1.12 (0.83, 1.49)

2.10 (1.36, 3.24)

< 0.001

 Hs-cTnT

  Model 1

Ref

1.31 (0.71, 2.44)

3.71 (1.94, 7.08)

< 0.001

  Model 2

Ref

1.27 (0.66, 2.43)

2.92 (1.47, 5.80)

< 0.001

  1. Model 1 adjusted for age and sex
  2. Model 2 adjusted for age, sex, race, current smoker, systolic blood pressure, diastolic blood pressure, body mass index, total cholesterol, high-density lipid cholesterol, estimated glomerular filtration rate, prediabetes status, antihypertensive medication use, antiplatelet medication use and statin use
  3. Hs high sensitivity, cTnT cardiac Troponin T, cTnI cardiac Troponin I, LOD limits of detection, 99th URL 99th percentile upper reference limit
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Cardiovascular Diabetology

ISSN: 1475-2840