Skip to main content

Table 2 Hazard ratios of triglyceride-glucose index tertiles for outcomes in the study participants

From: High triglyceride-glucose (TyG) index is associated with poor prognosis of heart failure with preserved ejection fraction

  

Model 1

   

Model 2

   

Model 3

  

Outcomes

Variables

HR

95%CI

P-value

 

HR

95%CI

P-value

 

HR

95%CI

P-value

All-cause death

TyG index*

1.41

1.06–1.88

0.018

 

1.45

1.10–1.92

0.008

 

1.46

1.10–1.96

0.009

 

Tertile 1

Reference

   

Reference

   

Reference

  
 

Tertile 2

0.90

0.68–1.19

0.452

 

0.92

0.71–1.20

0.550

 

1.00

0.77–1.30

0.969

 

Tertile 3

1.44

1.10–1.90

0.009

 

1.45

1.12–1.86

0.004

 

1.53

1.19–1.98

< 0.001

 

P for trend

  

0.011

   

0.029

   

0.038

CV death

TyG index*

1.43

1.08–1.89

0.010

 

1.43

1.07–1.90

0.016

 

1.49

1.13–1.97

0.005

 

Tertile 1

Reference

   

Reference

   

Reference

  
 

Tertile 2

0.92

0.7–1.22

0.576

 

0.94

0.72–1.21

0.612

 

1.01

0.79–1.32

0.880

 

Tertile 3

1.45

1.10–1.90

0.007

 

1.44

1.12–1.85

0.004

 

1.52

1.19–1.96

< 0.001

 

P for trend

  

0.009

   

0.042

   

0.045

HF rehospitalization

TyG index*

1.30

1.03–1.63

0.021

 

1.28

1.02–1.61

0.031

 

1.29

0.97–1.72

0.071

 

Tertile 1

Reference

   

Reference

   

Reference

  
 

Tertile 2

1.00

0.79–1.26

0.981

 

0.95

0.77–1.18

0.681

 

1.07

0.77–1.49

0.698

 

Tertile 3

1.34

1.06–1.70

0.013

 

1.34

1.09–1.65

0.004

 

1.36

0.98–1.90

0.069

 

P for trend

  

0.013

   

0.041

   

0.077

  1. HR, hazard ratio; CI, confidence interval; TyG, triglyceride glucose index; * TyG index as a continuous variable
  2. Model 1 adjusted for age and sex
  3. Model 2 adjusted for model 1 variables plus BMI, SBP, HbA1c, HDL-C, Cr, Hb, cTnT,NT-proBNP, FT4, diabetes, hyperlipidemia, and atrial fibrillation
  4. Model 3 adjusted for model 2 variables plus LVEF, septal e’, PASP, TR velocity, LA diameter, LA pressure, RV diameter, and usage of insulin, metformin, SGLT2i and ACEI/ARB/ARNI