The neutrophil–lymphocyte ratio as a risk factor for all-cause and cardiovascular mortality among individuals with diabetes: evidence from the NHANES 2003–2016

Table 3 Subgroup analysis of the associations between NLR and mortality among diabetes

Characteristics	Lower NLR (≤ 3.48)	Higher NLR^#	p^#	p interaction	Higher NLR*	p*	p interaction
Characteristics	Lower NLR (≤ 3.48)	HR (95% CI)	p^#	p interaction	HR (95% CI)	p*	p interaction
Age, y				0.704			0.085
< 60	1	2.28 (1.15–4.51)	0.018		1.96 (0.55–6.95)	0.29
≥ 60	1	1.99 (1.58–2.51)	< 0.0001		2.97 (1.99–4.42)	< 0.0001
Sex				0.752			0.21
Female	1	2.08 (1.45–3.00)	< 0.0001		2.54 (1.40–4.58)	0.002
Male	1	2.03 (1.57–2.63)	< 0.0001		3.46 (2.18–5.50)	< 0.0001
Smoking status				0.888			0.734
Never	1	2.16 (1.49–3.12)	< 0.0001		2.72 (1.49–4.99)	0.001
Former/current	1	2.04 (1.58–2.64)	< 0.0001		3.06 (1.86–5.02)	< 0.0001
Drinking status				0.748			0.733
Never	1	2.21 (1.28–3.80)	0.004		3.47 (1.31–9.18)	0.012
Former/mild/moderate/heavy	1	2.03 (1.60–2.56)	< 0.0001		2.84 (1.86–4.35)	< 0.0001
Hypertension				0.597			0.622
No	1	2.10 (1.32–3.33)	0.002		5.09 (2.11–12.32)	< 0.001
Yes	1	2.06 (1.60–2.65)	< 0.0001		2.83 (1.88–4.27)	< 0.0001

^#All-cause mortality; *cardiovascular mortality. HRs were adjusted for adjusted for age, sex, race, BMI, smoking, drinking, hypertension, HDL, LDL, TG, TC, HbA1c, education level, family income-to-poverty ratio, and eGFR

ISSN: 1475-2840