Fig. 1

Relationships of SDF-1 with recurrent stroke, cardiovascular events and all-cause mortality in patients with ischemic stroke

Hazards ratios and 95% confidence intervals derived from restricted cubic spline regression, with knots placed at the 5th, 35th, 65th, and 95th percentiles of the SDF-1 levels distribution. The reference point is the midpoint of the reference group for the categorical analysis. Hazard ratios were adjusted for the same variables as Model 3. Panel A: Recurrent Stroke at 1 year in ischemic stroke with diabetes (P for linearity = 0.005); Panel B: Recurrent Stroke at 1 year in ischemic stroke without diabetes (P for linearity = 0.49); Panel C: Cardiovascular events at 1 year in ischemic stroke with diabetes (P for linearity = 0.02). Panel D: Cardiovascular events at 1 year in ischemic stroke without diabetes (P for linearity = 0.11). Panel E: All-cause mortality at 1 year in ischemic stroke with diabetes (P for linearity = 0.09). Panel F: All-cause mortality at 1 year in ischemic stroke without diabetes (P for linearity = 0.34)