Table 1 Clinical characteristics of hospital admissions for heart transplantation among patients with and without type 2 diabetes mellitus (T2D) in Spain, 2002–2021
Year | 2002–2005 | 2006–2009 | 2010–2013 | 2014–2017 | 2018–2021 | P trend |
|---|---|---|---|---|---|---|
T2D | ||||||
N (%)* | 171(19.19) | 181(19.87) | 154(17.43) | 156(20.95) | 186(19.15) | 0.388 |
Women, n (%) | 25(14.62) | 28(15.47) | 20(12.99) | 21(13.46) | 29(15.59) | 0.947 |
Age, mean (SD) | 57.68(6.13) | 59.83(7.91) | 58.34(6.8) | 59.58(6.89) | 59.27(7.17) | 0.025 |
35–49 years, n (%) | 15(8.77) | 19(10.5) | 18(11.69) | 16(10.26) | 19(10.22) | 0.166 |
50–59 years, n (%) | 82(47.95) | 63(34.81) | 65(42.21) | 53(33.97) | 65(34.95) | |
≥ 60 years, n (%) | 74(43.27) | 99(54.7) | 71(46.1) | 87(55.77) | 102(54.84) | |
CCI, mean (SD) | 1.49(0.81) | 1.58(0.93) | 1.64(0.87) | 2.06(1.24) | 2.28(0.92) | < 0.001 |
CCI = 0, n (%) | 13(7.6) | 16(8.84) | 10(6.49) | 10(6.41) | 3(1.61) | < 0.001 |
CCI = 1, n (%) | 83(48.54) | 79(43.65) | 61(39.61) | 46(29.49) | 30(16.13) | |
CCI ≥ 2, n (%) | 75(43.86) | 86(47.51) | 83(53.9) | 100(64.1) | 153(82.26) | |
Obesity, n(%) | 13(7.6) | 6(3.31) | 13(8.44) | 9(5.77) | 23(12.37) | 0.020 |
Pulmonary hypertension, n(%) | 24(14.04) | 16(8.84) | 33(21.43) | 20(12.82) | 30(16.13) | 0.022 |
Valvular heart disease, n(%) | 19(11.11) | 22(12.15) | 23(14.94) | 28(17.95) | 38(20.43) | 0.081 |
Dilated cardiomyopathy, n(%) | 104(60.82) | 94(51.93) | 96(62.34) | 94(60.26) | 123(66.13) | 0.084 |
Ischemic heart disease, n(%) | 101(59.06) | 120(66.3) | 79(51.3) | 82(52.56) | 97(52.15) | 0.020 |
Congenital heart disease, n(%) | 0(0) | 0(0) | 3(1.95) | 4(2.56) | 3(1.61) | 0.097 |
NO DIABETES | ||||||
N | 757 | 762 | 621 | 739 | 702 | |
Women, n (%) | 126(16.64) | 181(23.75) | 159(25.6) | 185(25.03) | 189(26.92) | < 0.001 |
Age, mean (SD) | 53.97(8.52) | 55.64(9.22) | 55.29(8.82) | 54.97(9.26) | 55.32(8.89) | 0.004 |
35–49 years, n (%) | 215(28.4) | 187(24.54) | 157(25.28) | 206(27.88) | 190(27.07) | 0.008 |
50–59 years, n (%) | 327(43.2) | 295(38.71) | 232(37.36) | 274(37.08) | 254(36.18) | |
≥ 60 years, n (%) | 215(28.4) | 280(36.75) | 232(37.36) | 259(35.05) | 258(36.75) | |
CCI, mean (SD) | 1.45(0.8) | 1.49(0.83) | 1.54(0.83) | 1.77(0.94) | 2.02(0.95) | < 0.001 |
CCI = 0, n (%) | 59(7.79) | 63(8.27) | 37(5.96) | 37(5.01) | 22(3.13) | < 0.001 |
CCI = 1, n (%) | 379(50.07) | 353(46.33) | 298(47.99) | 274(37.08) | 185(26.35) | |
CCI ≥ 2, n (%) | 319(42.14) | 346(45.41) | 286(46.05) | 428(57.92) | 495(70.51) | |
Obesity, n(%) | 19(2.51) | 23(3.02) | 20(3.22) | 29(3.92) | 39(5.56) | 0.022 |
Pulmonary hypertension, n(%) | 107(14.13) | 110(14.44) | 97(15.62) | 96(12.99) | 80(11.4) | 0.208 |
Valvular heart disease, n(%) | 125(16.51) | 115(15.09) | 107(17.23) | 183(24.76) | 166(23.65) | < 0.001 |
Dilated cardiomyopathy, n(%) | 499(65.92) | 486(63.78) | 392(63.12) | 462(62.52) | 443(63.11) | 0.689 |
Ischemic heart disease, n(%) | 360(47.56) | 351(46.06) | 250(40.26) | 301(40.73) | 256(36.47) | < 0.001 |
Congenital heart disease, n(%) | 12(1.59) | 17(2.23) | 18(2.9) | 33(4.47) | 43(6.13) | < 0.001 |