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Table 1 Baseline and the follow-up characteristics of the study participants

From: Elevated high-sensitivity C-reactive protein levels increase the risk of new-onset cardiac conduction disorders

 

Overall

hsCRP ≤ 3 mg/L

hsCRP > 3 mg/L

P value

Participant (%)

86,234 (100)

70,002 (81.17)

16,232 (18.83)

 

Age (year)

50.57 ± 11.88

49.76 ± 11.72

54.13 ± 11.93

 < 0.0001

Male [n (%)]

67,665 (78.47)

55,317 (79.02)

12,348 (76.07)

 < 0.0001

BMI (kg/m2)

25.07 ± 3.46

24.93 ±  3.38

25.66 ± 3.71

 < 0.0001

TC (mmol/L)

4.95 ± 1.14

4.95 ± 1.14

4.97 ± 1.11

0.045

UA (umol/L)

287.08 ± 82.65

287.04 ±  80.74

287.28 ± 90.42

0.735

eGFR (ml/min/1.73m2)

72.32 ± 25.25

71.85 ± 24.58

74.34 ± 27.85

 < 0.0001

hsCRP (mg/L)

0.80 (0.30 ~ 2.11)

0.58 (0.23 ~ 1.19)

6.30 (4.12 ~ 9.20)

 < 0.0001

FBG (mmol/L)

5.45 ± 1.62

5.42 ± 1.52

5.57 ± 1.94

 < 0.0001

SBP (mmHg)

130.23 ± 20.62

129.56 ±  20.31

133.10 ± 21.68

 < 0.0001

DBP (mmHg)

83.38 ±  11.67

83.19 ± 11.58

84.21 ± 11.98

 < 0.0001

Smoking [n (%)]

33,835 (39.24)

28,490 (40.70)

5345 (32.93)

 < 0.0001

Drinking [n (%)]

34,921 (40.50)

29,577 (42.25)

5344 (32.92)

 < 0.0001

Physical activity [n (%)]

76,734 (88.98)

63,306 (90.43)

13,428 (82.73)

 < 0.0001

Proportions of relevant diseases or taking relevant medications at baseline

 Myocardial Infarction [n (%)]

965 (1.12)

732 (1.05)

233 (1.44)

 < 0.0001

 Hypertension [n (%)]

36,992 (42.90)

28,869 (41.24)

8123 (50.04)

 < 0.0001

 Diabetes [n (%)]

7659 (8.88)

5708 (8.15)

1951 (12.02)

 < 0.0001

 Antihypertensive drugs [n (%)]

8891 (10.31)

6820 (9.74)

2071 (12.76)

 < 0.0001

 Hypoglycemic drugs [n (%)]

1915 (2.22)

1467 (2.10)

448 (2.76)

 < 0.0001

 Lipid-lowering drugs [n (%)]

757 (0.88)

559 (0.80)

198 (1.22)

 < 0.0001

Proportions of relevant diseases or taking relevant medications during follow-up

 Myocardial infarction [n (%)]

1426 (1.65)

1016 (1.45)

410 (2.52)

 < 0.0001

 Hypertension [n (%)]

28,728 (33.31)

23,608 (33.72)

5120 (31.54)

 < 0.0001

 Diabetes [n (%)]

11,943 (13.85)

9336 (13.34)

2607 (16.06)

 < 0.0001

 Antihypertensive drugs [n (%)]

12,843 (14.89)

9640 (13.77)

3203 (19.73)

 < 0.0001

 Hypoglycemic drugs [n (%)]

4778 (5.54)

3285 (4.69)

1493 (9.19)

 < 0.0001

 Lipid-lowering drugs [n (%)]

2087 (2.42)

1530 (2.18)

557 (3.43)

 < 0.0001

  1. The measurement data of normal distribution were expressed as mean ± SD. The measurement data of skewed distribution were expressed as median (p25 ~ p75), and the counting data were expressed as number of cases (%). BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; hsCRP, high sensitivity C reactive protein; SBP, systolic blood pressure; TC, cholesterol; UA, uric acid
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Cardiovascular Diabetology

ISSN: 1475-2840