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Table 3 Association of cumulative RC with CVD in hypertensive participants and non-hypertensive participants

From: Cumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study

Cum-RC

Case/Total

Incidence density, per 1000 person-years

Model 1

Model 2

Model 3

G4*(≥ 54.66 mg/dl)

257/3433

7.25

1.45(1.21,1.75)

1.30(1.08,1.57)

1.27(1.03,1.57)

G3*(39.57-54.65 mg/dl)

209/3724

5.42

1.05(0.87,1.28)

0.97(0.79,1.17)

0.95(0.78,1.17)

G2*(26.40-39.56 mg/dl)

203/3583

5.50

1.08(0.89,1.31)

1.01(0.83,1.23)

1.00(0.82,1.22)

G1*(< 26.40 mg/dl)

198/3609

5.32

1.00 (Ref.)

1.00 (Ref.)

1.00 (Ref.)

G1(< 26.40 mg/dl)

317/3587

8.77

1.65(1.38,1.97)

1.28(1.06,1.53)

1.28(1.06,1.53)

G2(26.40-39.56 mg/dl)

348/3587

9.65

1.91(1.60,2.27)

1.39(1.16,1.67)

1.38(1.15,1.66)

G3(39.57-54.65 mg/dl)

354/3588

9.86

2.00(1.67,2.38)

1.44(1.20,1.72)

1.42(1.17,1.71)

G4(≥ 54.66 mg/dl)

425/3587

11.87

2.35(1.99,2.78)

1.67(1.40,1.99)

1.63(1.32,2.00)

P-trend

  

< 0.0001

< 0.0001

< 0.0001

  1. G1*-G4*were participants without hypertension;G1-G4 were participants with hypertension
  2. Model 1: adjusted for age and sex
  3. Model 2: included variables in model 1 and further SBP, LDL-C, HDL-C, BMI, hs-CRP, eGFR, family history of CVD, smoking status, alcohol consumption, physical exercise habits, diabetes, the use of antihypertensive drugs, the use of glucose-lowering drugs, and the use of lipid-lowering drugs
  4. Model 3: included variables in model 2 and further the RC at baseline
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Cardiovascular Diabetology

ISSN: 1475-2840