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Table 1 Baseline characteristics of participants with hypertension by cumulative RC quartiles

From: Cumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study

 

Total

Q1

(< 26.40 mg/dl)

Q2

(26.40-39.56 mg/dl)

Q3

(39.57-54.65 mg/dl)

Q4

(≥ 54.66 mg/dl)

*P value

Participants

14,349

3587

3587

3588

3587

/

Age (years)

56.05 ± 10.29

55.59 ± 10.81

56.07 ± 9.38

56.11 ± 10.18

56.44 ± 10.74

0.02

Male, N (%)

11,771(82.0)

3041(84.8)

2974 (82.9)

2856(79.6)

2900(80.8)

< 0.01

BMI (kg/m2 )

26.06 ± 3.41

25.47 ± 3.34

26.17 ± 3.45

26.13 ± 3.46

26.45 ± 3.30

< 0.01

SBP (mmHg)

141.77 ± 19.08

142.09 ± 19.56

140.96 ± 19.42

141.85 ± 19.12

142.19 ± 8.16

< 0.01

DBP (mmHg)

89.66 ± 10.87

89.14 ± 10.93

89.63 ± 11.07

89.93 ± 10.45

89.95 ± 10.99

< 0.01

HDL-C (mg/dl)

57.44 ± 15.87

60.53 ± 15.43

56.71 ± 15.02

56.31 ± 15.72

56.21 ± 16.87

< 0.01

LDL-C (mg/dl)

101.20 ± 31.91

103.54 ± 27.54

104.99 ± 28.52

101.02 ± 32.71

95.25 ± 37.10

< 0.01

*TG (mg/dl)

53.90(37.73–80.85)

36.58(26.95–48.90)

53.90(40.43–73.54)

53.90(42.35–85.86)

77.00(51.98-120.89)

< 0.01

*RC2006(mg/dl)

45.43(25.03–71.61)

20.02(14.25–28.49)

38.50(26.56–52.75)

56.21(40.81–73.15)

84.70(62.37-112.42)

< 0.01

*RC2008(mg/dl)

32.34(19.63–53.90)

16.48(11.94–21.56)

29.26(22.33–36.96)

45.43(31.96–57.37)

67.76(46.20-87.01)

< 0.01

*RC2010(mg/dl)

29.65(16.56–54.29)

16.56(11.55–23.87)

26.95(16.56–41.20)

36.19(20.02–57.75)

61.98(37.35–93.17)

< 0.01

*Cum-RC(mg/dl)

39.63(26.49–55.49)

19.72(15.64–23.17)

32.92(29.79–36.04)

46.89(43.17–50.59)

68.70(61.03–80.43)

< 0.01

FPG (mmol/L)

5.92 ± 1.95

5.65 ± 1.48

5.87 ± 1.69

5.98 ± 1.79

6.18 ± 2.60

< 0.01

*hs-CRP (mg/L)

1.40(0.62–3.20)

1.40(0.70-3.00)

1.30(0.55-3.00)

1.40(0.60–3.26)

1.30(0.66–3.63)

< 0.01

eGFR(ml/min/1.73m2)

84.73 ± 18.76

79.39 ± 18.64

83.78 ± 18.58

87.06 ± 18.35

88.70 ± 18.10

< 0.01

Current smoker, N (%)

5434(37.9)

1127(31.4)

1389(38.7)

1443(40.2)

1475(41.1)

< 0.01

Alcohol drinker, N (%)

4999(34.8)

1037(28.9)

1233(34.4)

1331(37.1)

1398(39.0)

< 0.01

Physical activity, N (%)

2151(15.0)

509(14.2)

606(16.9)

564(15.7)

472(13.2)

< 0.01

Education, N (%)

2669(18.6)

591(16.5)

776(21.6)

681(19.0)

621(17.3)

< 0.01

Diabetes, N (%)

2335(16.3)

415(11.6)

535(14.9)

608(16.9)

777(21.7)

< 0.01

Antihypertensive drugs, N (%)

4372(30.5)

980(27.3)

1118(31.2)

1117(31.1)

1157(32.3)

< 0.01

Hypoglycemic drugs, N (%)

1164(8.11)

185(5.16)

266(7.42)

309(8.61)

404(11.3)

< 0.01

Lipid-lowering drugs, N (%)

195(1.36)

16(0.45)

39(1.09)

57(1.59)

83(2.31)

< 0.01

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FPG fasting plasma glucose, TG triglyceride, hs-CRP high-sensitivity C reactive protein,eGFR estimated glomerular filtration rate, RC remant cholesterol, Cum-RC cumulative remant cholesterol
  2. *P value, comparison of baseline characteristics between diferent Cum-RC groups
  3. *TG, hs-CRP, RC2006, RC2008, RC2010 and Cum-RC were expressed by median (IQR)