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Table 3 Univariable and multivariable analysis between first-pass perfusion parameters and clinical indices in T2DM patients

From: Subclinical left ventricular deformation and microvascular dysfunction in T2DM patients with and without peripheral neuropathy: assessed by 3.0 T cardiac magnetic resonance imaging

 

Upslope

Max SI

TTM (s)

Univariable

Multivariable

Univariable

Multivariable

Univariable

Multivariable

r

β

p

r

β

p

r

β

p

DPN

− 0.487*

− 0.360

0.021

− 3.934*

− 2.503

0.031

− 0.115

  

Retinopathy

− 0.289

  

− 1.374

  

2.617

  

CKD

− 0.402*

− 0.399

0.043

− 4.741*

− 4.057

0.005

− 4.388

  

Dyslipidemia

− 0.296*

− 0.114

0.104

− 3.092*

− 2.569

0.018

1.317

  

Age (years)

0.002

  

0.031

  

− 0.057

  

Sex (male = 1)

− 0.840*

− 0.885

< 0.001

− 4.159*

− 3.556

0.001

8.352*

11.073

< 0.001

BMI (kg/m2)

− 0.051*

− 0.057

0.007

− 0.252

  

− 0.045

  

HR (beats/min)

0.028*

0.025

< 0.001

0.065

  

− 0.397*

− 0.346

0.001

SBP (mmHg)

0.002

  

0.026

  

− 0.130*

− 0.138

0.022

Smoking

− 0.427*

0.058

0.449

− 1.106

  

5.263*

− 0.093

0.291

LVM (g)

− 0.013*

0.015

0.861

− 0.069*

0.005

0.951

0.087*

0.020

0.833

HbA1c (%)

− 0.007

  

0.272

  

1.121*

0.093

0.224

Diabetic duration (long = 1)

− 0.202

− 0.053

0.438

0.412

− 0.094

0.197

− 2.096

0.076

0.319

Statin

− 0.027

  

− 1.894

  

− 0.144

  

Biguanides

0.178*

− 0.093

0.171

− 2.590*

− 0.104

0.151

2.689

  

Sulfonylureas

− 0.310*

− 0.074

0.285

− 1.860

  

2.223

  

α-Glucosidase inhibitor

− 0.449*

− 0.492

0.001

− 2.908*

− 2.388

0.025

2.569

  

GLP-1/DDP-4 inhibitor

0.157

  

0.406

  

1.211

  

Insulin

− 0.265

  

− 1.794

  

0.788

  

ACEI/ARB

− 0.001

  

0.886

  

− 2.900

  

β-Blocker

0.227

  

0.770

  

− 6.094*

− 0.042

0.579

Calcium channel blocker

0.120

  

0.451

  

− 3.590

  

R2

 

0.364

  

0.235

  

0.273

 
  1. Variables with p < 0.1 in the univariable analysis as well as diabetic duration were included in the multivariable liner regression model
  2. Abbreviations as in Tables 1 and 2; long = 1 means patients with long term duration > 5 years
  3. * p < 0.1
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Cardiovascular Diabetology

ISSN: 1475-2840