Skip to main content

Table 2 Multivariable MR analysis outcomes

From: Causal associations between type 1 diabetes mellitus and cardiovascular diseases: a Mendelian randomization study

Potential confounding factors

Outcome

nsnp

Pval

OR

95%CI

HDL

PAS

21

8.40E-07

1.1

1.06–1.15

CAS

21

0.011

1.04

1.01–1.08

LDL

PAS

19

8.50E-08

1.13

1.08–1.18

CAS

19

0.002

1.06

1.02–1.09

Total cholesterol

PAS

19

1.70E-07

1.12

1.07–1.16

CAS

19

0.001

1.06

1.02–1.09

Triglycerides

PAS

21

8.30E-08

1.12

1.07–1.17

CAS

21

0.001

1.05

1.02–1.08

apo A

PAS

19

1.60E-07

1.08

1.05–1.11

CAS

19

0.005

1.03

1.01–1.06

apo B

PAS

25

3.40E-06

1.09

1.05–1.13

CAS

25

0.018

1.04

1.01–1.07

Lipoprotein A

PAS

35

6.60E-06

1.08

1.05–1.12

CAS

35

0.007

1.04

1.01–1.06

T2DM

PAS

32

1.70E-08

1.08

1.05–1.11

CAS

32

0.002

1.03

1.01–1.06

Hypertension

PAS

31

3.00E-06

1.08

1.04–1.11

CAS

31

0.029

1.03

1.00–1.05

Smoking previous

PAS

33

3.00E-06

1.08

1.05–1.12

CAS

33

0.003

1.04

1.01–1.06

Smoking current

PAS

33

2.60E-05

1.08

1.04–1.12

CAS

33

0.003

1.04

1.01–1.06

BMI

PAS

20

5.00E-08

1.1

1.06–1.14

CAS

20

0.001

1.04

1.02–1.07

IL-6

PAS

35

7.60E-07

1.09

1.05–1.12

CAS

35

0.001

1.04

1.02–1.06

CRP

PAS

21

8.20E-09

1.11

1.07–1.15

CAS

21

0.005

1.05

1.01–1.08

  1. Notes: HDL, high density lipoprotein; LDL, low density lipoprotein; apo A, apoprotein A; apo B, apoprotein B; T2DM, type 2 diabetes mellitus; BMI, body mass index; IL-6, interleukin-6; CRP, C-reactive protein, PAS, peripheral atherosclerosis and CAS, coronary atherosclerosis
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840