Variables | Overall | non-AKI | AKI | p value |
---|---|---|---|---|
Number of patients | 1393 | 239 | 1154 | Â |
Male,n(%) | 822 (59.0) | 123 (51.5) | 699 (60.6) | 0.011 |
Age,years,(median [IQR]) | 71.00 [60.00, 81.00] | 71.00 [59.00, 82.00] | 71.00 [60.00, 81.00] | 0.417 |
Race,n(%) | Â | Â | Â | 0.1 |
White | 915 (65.7) | 156 (65.3) | 759 (65.8) | Â |
Black | 97 (7.0) | 20 (8.4) | 77 (6.7) | Â |
Asian | 32 (2.3) | 10 (4.2) | 22 (1.9) | Â |
Others | 349 (25.1) | 53 (22.2) | 296 (25.6) | Â |
BMI,kg/m2,n(%) | Â | Â | Â | 0.037 |
 <30 | 415 (29.8) | 87 (36.4) | 328 (28.4) |  |
 >=30 | 244 (17.5) | 34 (14.2) | 210 (18.2) |  |
 Missing | 734 (52.7) | 118 (49.4) | 616 (53.4) |  |
ASPIII (median [IQR]) | 43.00 [32.00, 55.00] | 34.00 [26.00, 45.00] | 45.00 [34.00, 58.00] | < 0.001 |
SAPIII (median [IQR]) | 36.00 [29.00, 45.00] | 31.00 [24.50, 37.00] | 37.00 [30.00, 46.00] | < 0.001 |
SIRS score (median [IQR]) | 3.00 [2.00, 3.00] | 2.00 [2.00, 3.00] | 3.00 [2.00, 3.00] | 0.02 |
SOFA score (median [IQR]) | 4.00 [2.00, 7.00] | 3.00 [1.00, 4.50] | 5.00 [3.00, 8.00] | < 0.001 |
Vital Signs | Â | Â | Â | Â |
HR (median [IQR]) | 87.00 [75.00, 101.00] | 86.00 [74.50, 101.50] | 87.00 [76.00, 101.00] | 0.403 |
SBP,mmhg,n(%) | Â | Â | Â | 0.714 |
 < 90 | 13 (0.9) | 1 (0.4) | 12 (1.0) |  |
 >140 | 158 (11.3) | 30 (12.6) | 128 (11.1) |  |
 90–140 | 496 (35.6) | 87 (36.4) | 409 (35.4) |  |
 Missing | 726 (52.1) | 121 (50.6) | 605 (52.4) |  |
DBP,mmhg,n(%) | Â | Â | Â | 0.768 |
 < 60 | 94 (6.7) | 14 (5.9) | 80 (6.9) |  |
 > 90 | 53 (3.8) | 11 (4.6) | 42 (3.6) |  |
 60–90 | 520 (37.3) | 93 (38.9) | 427 (37.0) |  |
 Missing | 726 (52.1) | 121 (50.6) | 605 (52.4) |  |
Laboratory tests | Â | Â | Â | Â |
Lymphocyte,%,n(%) |  |  |  | < 0.001 |
 <7 | 281 (20.2) | 32 (13.4) | 249 (21.6) |  |
 > 18.8 | 202 (14.5) | 40 (16.7) | 162 (14.0) |  |
 11.50–18.80 | 253 (18.2) | 42 (17.6) | 211 (18.3) |  |
 7–11.50 | 274 (19.7) | 28 (11.7) | 246 (21.3) |  |
 Missing | 383 (27.5) | 97 (40.6) | 286 (24.8) |  |
Neutrophils,%,n(%) |  |  |  | < 0.001 |
 <69.8 | 211 (15.1) | 41 (17.2) | 170 (14.7) |  |
 > 85.9 | 277 (19.9) | 35 (14.6) | 242 (21.0) |  |
 69.8–79.60 | 251 (18.0) | 33 (13.8) | 218 (18.9) |  |
 79.60–85.90 | 271 (19.5) | 33 (13.8) | 238 (20.6) |  |
 Missing | 383 (27.5) | 97 (40.6) | 286 (24.8) |  |
Platelets,(K/uL),(median [IQR]) | 209.00 [161.00, 268.00] | 215.00 [167.00, 272.25] | 208.00 [160.00, 268.00] | 0.237 |
WBC (median [IQR]) | 10.30 [7.60, 13.80] | 10.10 [7.30, 12.88] | 10.40 [7.70, 14.00] | 0.052 |
RBC,m/uL,(median [IQR]) | 3.92 [3.41, 4.43] | 3.93 [3.40, 4.42] | 3.91 [3.41, 4.43] | 0.939 |
Hemoglobin,g/dL,(median [IQR]) | 11.70 [10.10, 13.20] | 11.90 [10.20, 13.20] | 11.60 [10.10, 13.30] | 0.352 |
PCO2,mmhg,(median [IQR]) | 41.00 [35.00, 48.00] | 41.00 [35.00, 48.00] | 40.00 [35.00, 48.00] | 0.721 |
PH (median [IQR]) | 7.39 [7.33, 7.44] | 7.39 [7.34, 7.42] | 7.39 [7.33, 7.44] | 0.996 |
PO2,mmhg,(median [IQR]) | 41.00 [35.00, 48.00] | 41.00 [35.00, 48.00] | 40.00 [35.00, 48.00] | 0.721 |
Albumin,g/dL(median [IQR]) | 3.30 [2.80, 3.70] | 3.50 [3.10, 3.82] | 3.30 [2.80, 3.70] | < 0.001 |
BUN,mg/dL(median [IQR]) | 22.00 [16.00, 35.00] | 20.00 [15.00, 30.50] | 22.00 [16.25, 36.00] | < 0.001 |
SCR, mg/dL,(median [IQR]) | 1.10 [0.80, 1.50] | 1.00 [0.80, 1.30] | 1.10 [0.80, 1.60] | < 0.001 |
UCR,mg/dL,n(%) |  |  |  | < 0.001 |
 < 48 | 134 (9.6) | 16 (6.7) | 118 (10.2) |  |
 > 122 | 135 (9.7) | 11 (4.6) | 124 (10.7) |  |
 48–78 | 127 (9.1) | 16 (6.7) | 111 (9.6) |  |
 78–122 | 132 (9.5) | 9 (3.8) | 123 (10.7) |  |
 Missing | 865 (62.1) | 187 (78.2) | 678 (58.8) |  |
HDL,mg/dL,n(%) |  |  |  | < 0.001 |
 < 33 | 248 (17.8) | 31 (13.0) | 217 (18.8) |  |
 > 53 | 238 (17.1) | 63 (26.4) | 175 (15.2) |  |
 33–42 | 272 (19.5) | 57 (23.8) | 215 (18.6) |  |
 42–53 | 258 (18.5) | 51 (21.3) | 207 (17.9) |  |
 Missing | 377 (27.1) | 37 (15.5) | 340 (29.5) |  |
LDL,mg/dL,n(%) |  |  |  | < 0.001 |
 < 55 | 249 (17.9) | 32 (13.4) | 217 (18.8) |  |
 > 103 | 245 (17.6) | 54 (22.6) | 191 (16.6) |  |
 55–76 | 255 (18.3) | 56 (23.4) | 199 (17.2) |  |
 76–103 | 250 (17.9) | 58 (24.3) | 192 (16.6) |  |
 Missing | 394 (28.3) | 39 (16.3) | 355 (30.8) |  |
TG,mg/dL,(median [IQR]) | 113.00 [84.00, 164.00] | 105.00 [80.50, 155.50] | 114.00 [84.25, 166.00] | 0.046 |
TC,mg/dL,n(%) |  |  |  | < 0.001 |
 <116 | 257 (18.4) | 30 (12.6) | 227 (19.7) |  |
 >174 | 259 (18.6) | 59 (24.7) | 200 (17.3) |  |
 116–145 | 275 (19.7) | 62 (25.9) | 213 (18.5) |  |
 145–174 | 253 (18.2) | 55 (23.0) | 198 (17.2) |  |
 Missing | 349 (25.1) | 33 (13.8) | 316 (27.4) |  |
Glucose,mg/dL,(median [IQR]) | 129.00 [106.00, 172.00] | 126.00 [103.00, 164.00] | 130.00 [107.00, 173.00] | 0.117 |
HbA1c%,n(%) | Â | Â | Â | 0.105 |
 < 5.7 | 275 (19.7) | 57 (23.8) | 218 (18.9) |  |
 > 6.4 | 261 (18.7) | 46 (19.2) | 215 (18.6) |  |
 5.7–6.4 | 287 (20.6) | 54 (22.6) | 233 (20.2) |  |
 Missing | 570 (40.9) | 82 (34.3) | 488 (42.3) |  |
TNTµg/L,n(%) |  |  |  | 0.286 |
 <0.06 | 202 (14.5) | 33 (13.8) | 169 (14.6) |  |
 >0.975 | 203 (14.6) | 32 (13.4) | 171 (14.8) |  |
 0.06–0.25 | 208 (14.9) | 27 (11.3) | 181 (15.7) |  |
 0.25–0.975 | 198 (14.2) | 34 (14.2) | 164 (14.2) |  |
 Missing | 582 (41.8) | 113 (47.3) | 469 (40.6) |  |
CKMB(IU/L),n(%) |  |  |  | < 0.001 |
 < 3 | 180 (12.9) | 33 (13.8) | 147 (12.7) |  |
 > 18 | 280 (20.1) | 24 (10.0) | 256 (22.2) |  |
 3–6 | 2 (0.1) | 0 (0.0) | 2 (0.2) |  |
 6–18 | 13 (0.9) | 1 (0.4) | 12 (1.0) |  |
 Missing | 918 (65.9) | 181 (75.7) | 737 (63.9) |  |
NT-proBNP,pg/mL,n(%) | Â | Â | Â | 0.401 |
 <1632 | 78 (5.6) | 17 (7.1) | 61 (5.3) |  |
 >10521 | 78 (5.6) | 8 (3.3) | 70 (6.1) |  |
 1632–3955 | 78 (5.6) | 15 (6.3) | 63 (5.5) |  |
 3955–10,521 | 77 (5.5) | 13 (5.4) | 64 (5.5) |  |
 Missing | 1082 (77.7) | 186 (77.8) | 896 (77.6) |  |
CRP(mg/L),n(%) | Â | Â | Â | 0.241 |
 < 13.95 | 41 (2.9) | 8 (3.3) | 33 (2.9) |  |
 >134.4 | 41 (2.9) | 5 (2.1) | 36 (3.1) |  |
 13.95–57.90 | 41 (2.9) | 6 (2.5) | 35 (3.0) |  |
 57.90–134.4 | 40 (2.9) | 2 (0.8) | 38 (3.3) |  |
 Missing | 1230 (88.3) | 218 (91.2) | 1012 (87.7) |  |
Potassium,mmol/L,(median [IQR]) | 4.10 [3.80, 4.50] | 4.00 [3.70, 4.40] | 4.20 [3.80, 4.60] | 0.016 |
Sodium,mmol/L,(median [IQR]) | 139.00 [136.00, 141.00] | 139.00 [136.00, 141.00] | 139.00 [136.00, 142.00] | 0.69 |
TyG index,(median [IQR]) | 4.82 [4.61, 5.07] | 4.78 [4.57, 5.01] | 4.83 [4.63, 5.08] | 0.016 |
Comorbidities,n (%) | Â | Â | Â | Â |
AF,n(%) | 613 (44.0) | 82 (34.3) | 531 (46.0) | 0.001 |
AMI,n(%) | 485 (34.8) | 80 (33.5) | 405 (35.1) | 0.686 |
CKD,n(%) | 383 (27.5) | 43 (18.0) | 340 (29.5) | < 0.001 |
COPD,n(%) | 164 (11.8) | 26 (10.9) | 138 (12.0) | 0.718 |
Dyslipidemia,n(%) | 658 (47.2) | 117 (49.0) | 541 (46.9) | 0.608 |
Diabetes,n(%) | 524 (37.6) | 77 (32.2) | 447 (38.7) | 0.069 |
Hypertension,n(%) | 494 (35.5) | 103 (43.1) | 391 (33.9) | 0.008 |
PCI,n(%) | 189 (13.6) | 41 (17.2) | 148 (12.8) | 0.094 |
CABG,n(%) | 69 (5.0) | 10 (4.2) | 59 (5.1) | 0.661 |
Medications | Â | Â | Â | Â |
ARNI,n(%) | 11 (0.8) | 1 (0.4) | 10 (0.9) | 0.756 |
ACEI,n(%) | 634 (45.5) | 120 (50.2) | 514 (44.5) | 0.126 |
ARB,n(%) | 135 (9.7) | 28 (11.7) | 107 (9.3) | 0.297 |
Beta blocker,n(%) | 1090 (78.2) | 183 (76.6) | 907 (78.6) | 0.545 |
Digoxin ,n(%) | 165 (11.8) | 22 (9.2) | 143 (12.4) | 0.201 |
Loop diuretics,n(%) | 1129 (81.0) | 154 (64.4) | 975 (84.5) | < 0.001 |