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Table 1 Baseline characteristics of participants according to the tertiles of the TyG index

From: Triglyceride-glucose index in the prediction of adverse cardiovascular events in patients without diabetes mellitus after coronary artery bypass grafting: a multicenter retrospective cohort study

Variables

Tertile 1 (n = 277)

Tertile 2 (n = 276)

Tertile 3 (n = 277)

p-value

TyG index

8.04 ± 0.26

8.57 ± 0.12

9.17 ± 0.33

< 0.001

General conditions

 Age (years)

63.57 ± 7.98

62.93 ± 7.88

61.88 ± 8.58

0.048

 Male, n (%)

218 (78.7)

206 (74.6)

193 (69.7)

0.051

 BMI (kg/m2)

24.48 ± 3.41

26.00 ± 3.83

26.31 ± 3.51

< 0.001

 LVEF (%)

58.56 ± 10.30

59.01 ± 9.63

58.86 ± 10.56

0.866

 Prediabetes, n (%)

19 (6.9)

55 (19.9)

124 (44.8)

< 0.001

 Previous MI, n (%)

49 (17.7)

53 (19.2)

68 (24.5)

0.110

 Previous stroke, n (%)

33 (11.9)

34 (12.3)

43 (15.5)

0.390

 Previous PCI, n (%)

27 (9.7)

29 (10.5)

23 (8.3)

0.669

 Left main disease, n (%)

54 (19.5)

61 (22.1)

76 (27.4)

0.077

 Multivessel disease, n (%)

257 (92.8)

254 (92.0)

263 (94.9)

0.365

Risk factors, n (%)

 Current smoking

86 (31.0)

71 (25.7)

85 (30.7)

0.306

 Current drinking

73 (26.4)

71 (25.7)

80 (28.9)

0.676

 FH-CAD

51 (18.4)

45 (16.3)

60 (21.7)

0.267

 Hypertension

153 (55.2)

157 (56.9)

183 (66.1)

0.020

 Hyperlipidemia

66 (23.8)

82 (29.7)

99 (35.7)

0.009

Surgical procedure

 Duration of surgery (min)

270.00 (235.00–310.00)

270.00 (230.00–313.75)

270.00 (240.00–325.00)

0.483

 OPCABG, n (%)

250 (90.3)

250 (90.6)

239 (86.3)

0.197

 Number of grafts

3.53 ± 1.01

3.65 ± 1.04

3.66 ± 0.98

0.259

 Use of arterial grafts, n (%)

264 (95.3)

264 (95.7)

266 (96.0)

0.917

  Left internal mammary artery, n (%)

248 (89.5)

243 (88.0)

249 (89.9)

0.760

  Right internal mammary artery, n (%)

25 (9.0)

30 (10.9)

26 (9.4)

0.741

  Radial artery, n (%)

10 (3.6)

12 (4.3)

11 (4.0)

0.906

  Complete revascularization, n (%)

260 (93.9)

254 (92.0)

259 (93.5)

0.665

  Use of IABP, n (%)

10 (3.6)

12 (4.3)

11 (4.0)

0.906

Laboratory tests

 FPG (mmol/L)

4.66 (4.33–5.07)

5.02 (4.71–5.61)

5.57 (4.98–6.01)

< 0.001

 TC (mmol/L)

3.85 (3.20–4.50)

4.01 (3.50–4.97)

4.51 (3.83–5.14)

< 0.001

 TG (mmol/L)

0.87 (0.70–1.01)

1.30 (1.14–1.47)

1.96 (1.61–2.46)

< 0.001

 LDL-C (mmol/L)

2.20 (1.74–2.76)

2.55 (2.01–3.12)

2.69 (2.12–3.35)

< 0.001

 HDL-C (mmol/L)

1.19 ± 0.25

1.12 ± 0.29

1.08 ± 0.23

< 0.001

 eGFR (mL/min/1.73m2)

91.35 ± 13.15

90.63 ± 13.45

90.70 ± 13.61

0.787

Cardiovascular medications, n (%)

 Antiplatelet drugs

272 (98.2)

268 (97.1)

272 (98.2)

0.595

 Statins

227 (81.9)

237 (85.9)

226 (81.6)

0.329

 ACEI/ARB

102 (36.8)

117 (42.4)

121 (43.7)

0.218

 Beta-blockers

247 (89.2)

254 (92.0)

242 (87.4)

0.196

 Diuretics

  Loop diuretics

24 (8.7)

27 (9.8)

33 (11.9)

0.436

  Thiazide diuretics

40 (14.4)

38 (13.8)

48 (17.3)

0.463

  Mineralocorticoid receptor antagonists

46 (16.6)

39 (14.1)

50 (18.1)

0.450

EuroSCORE II

1.35 (0.97–2.34)

1.35 (0.99–2.44)

1.38 (0.95–2.10)

0.613

MACE, n (%)

39 (14.1)

45 (16.3)

80 (28.9)

< 0.001

  1. p values in bold are < 0.05
  2. TyG index triglyceride-glucose index, MI myocardial infarction, LVEF left ventricle ejection fraction, PCI percutaneous coronary intervention, FH-CAD family history of coronary artery disease, BMI body mass index, OPCABG off-pump coronary artery bypass grafting, IABP intra-aortic balloon pump, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, LDL-C low-density lipoprotein-cholesterol, HDL-C high-density lipoprotein-cholesterol, eGFR estimated glomerular filtration rate, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers, EuroSCORE European System for Cardiac Operative Risk Evaluation score, MACE major adverse cardiovascular event