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Table 1 Baseline characteristics of participants by cumulative TyG index quartile

From: Relationship between cumulative exposure to triglyceride-glucose index and heart failure: a prospective cohort study

 

Total

Quartiles of cumulative TyG index

P

Q1(22.11–32.06)

Q2(32.06–34.53)

Q3(34.53–37.60)

Q4(37.60-56.14)

N

56,149

14,037

14,038

14,037

14,037

-

Age, years

49.42 ± 11.93

45.07 ± 10.64

47.37 ± 11.62

51.15 ± 11.93

54.09 ± 11.43

< 0.01

Male, N (%)

43,013(76.6)

10,016(71.4)

11,219(79.9)

10,969(78.1)

10,809(77.0)

< 0.01

SBP, mmHg

129.88 ± 17.06

124.01 ± 15.82

128.67 ± 15.86

132.14 ± 17.04

134.69 ± 17.53

< 0.01

DBP, mmHg

83.68 ± 9.25

81.35 ± 9.21

83.59 ± 8.91

84.58 ± 9.21

85.21 ± 9.21

< 0.01

BMI, kg/m2

25.04 ± 3.16

24.07 ± 3.06

24.87 ± 3.13

25.32 ± 3.10

25.91 ± 3.07

< 0.01

WC, cm

87.35 ± 8.58

84.46 ± 8.55

86.89 ± 8.34

88.32 ± 8.35

89.72 ± 8.18

< 0.01

HDL-C, mmol/L

1.54 ± 0.32

1.59 ± 0.32

1.55 ± 0.30

1.53 ± 0.32

1.48 ± 0.33

< 0.01

LDL-C, mmol/L

2.50 ± 0.64

2.33 ± 0.64

2.49 ± 0.60

2.54 ± 0.63

2.63 ± 0.64

< 0.01

eGFR, ml/min/1.73m2

87.16 ± 17.67

90.39 ± 16.88

87.28 ± 18.46

85.64 ± 18.38

85.34 ± 16.41

< 0.01

TG, mmol/L

1.68 ± 1.26

1.07 ± 0.51

1.46 ± 0.71

1.79 ± 1.11

2.41 ± 1.84

< 0.01

FBG, mmol/L

5.56 ± 1.40

5.10 ± 0.68

5.36 ± 0.97

5.59 ± 1.33

6.18 ± 2.01

< 0.01

hs-CRP, mg/L

2.63 ± 3.70

2.61 ± 3.75

2.54 ± 3.90

2.66 ± 3.84

2.70 ± 3.28

< 0.01

TyG index2006

8.65 ± 0.69

8.22 ± 0.53

8.57 ± 0.58

8.74 ± 0.65

9.05 ± 0.71

< 0.01

TyG index2008

8.67 ± 0.69

8.20 ± 0.51

8.57 ± 0.51

8.77 ± 0.61

9.16 ± 0.71

< 0.01

TyG index2010

8.70 ± 0.68

8.31 ± 0.51

8.61 ± 0.56

8.78 ± 0.65

9.10 ± 0.71

< 0.01

CumTyG

35.02 ± 4.22

30.09 ± 1.63

33.29 ± 0.71

35.98 ± 0.88

40.70 ± 2.62

< 0.01

Current smoker, N (%)

21,496(38.3)

5556(39.6)

5651(40.3)

5311(37.8)

4978(35.5)

< 0.01

Current drinker, N (%)

19,735(35.1)

5005(35.7)

5090(36.3)

4890(34.8)

4750(33.8)

< 0.01

Physical activity, N (%)

8221(14.6)

1655(11.8)

1710(12.2)

2280(16.2)

2576(18.4)

< 0.01

History of myocardial infarction, N (%)

506(0.90)

87(0.62)

83(0.59)

118(0.84)

218(1.56)

< 0.01

History of arrhythmia, N (%)

2081(3.71)

469(3.34)

446(3.18)

538(3.83)

628(4.47)

< 0.01

Hypertension, N (%)

27,429(48.9)

4947(35.2)

6362(45.3)

7569(53.9)

8551(60.9)

< 0.01

Diabetes mellitus, N (%)

6511(11.6)

499(3.55)

996(7.10)

1733(12.3)

3283(23.4)

< 0.01

Hypoglycemic drugs, N (%)

9110(16.2)

1479(10.5)

2144(15.3)

2575(18.3)

2912(20.7)

< 0.01

Anti-hypertensive drugs, N (%)

3466(6.17)

255(1.82)

498(3.55)

860(6.13)

1853(13.2)

< 0.01

Lipid-lowering drugs, N (%)

1692(3.01)

248(1.77)

306(2.18)

417(2.97)

721(5.14)

< 0.01

  1. SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, WC waist circumference, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride, FBG fasting blood glucose, hs-CRP high-sensitivity C reactive protein, eGFR estimated glomerular filtration rate, TyG index triglyceride-glucose index