Skip to main content

Table 3 Subgroup Patient Characteristics and Clinical Laboratory Values

From: Endogenous estradiol contributes to vascular endothelial dysfunction in premenopausal women with type 1 diabetes

Variable

HBC (+)

HBC (-)

p-value

(n = 9)

(n = 9)

Demographics

   

Age (y)

25 ± 7

23 ± 3

0.308

 Time Since Diagnosis (y)

15 ± 10

13 ± 6

0.658

Height (cm)

166.3 ± 7.5

163.9 ± 6.9

0.484

Weight (kg)

80.2 ± 18.7

67.9 ± 18.3

0.177

BMI (kg/m2)

29.0 ± 6.4

25.2 ± 5.9

0.214

MAP (mm Hg)

91 ± 7

90 ± 6

0.949

Clinical Laboratory Values

   

CRP (mg/L)

4.8 ± 4.3

8.0 ± 11.7

0.466

TC (mg/dL)

192 ± 42

179 ± 29

0.460

HDL (mg/dL)

70 ± 22

63 ± 18

0.444

LDL (mg/dL)

95 ± 33

97 ± 32

0.867

TRIG (mg/dL)

103 ± 67

67 ± 23

0.152

TC/HDL ratio

3.0 ± 1.2

3.0 ± 0.9

0.947

HbA1c (%)

8.3 ± 2.1

8.9 ± 2.1

0.509

FBG (mg/dL) – M/P

142 ± 60

132 ± 67

0.731

FBG (mg/dL) – LF/A

158 ± 53

158 ± 70

0.988

Insulin (uIU/mL) – M/P

1.3 ± 1.5

7.0 ± 18.3

0.386

Insulin (uIU/mL) – LF/A

1.4 ± 1.7

5.5 ± 14.5

0.419

Estradiol (pg/mL) – M/P

17 ± 14 (5–45)

42 ± 31 (12–114)

0.041

Estradiol (pg/mL) – LF/A

21 ± 35 (5-112)

108 ± 64* (28–210)

0.002

LH (mIU/mL) – M/P

3 ± 3 (1–11)

5 ± 3 (1–9)

0.203

LH (mIU/mL) – LF/A

5 ± 5 (0–12)

14 ± 9* (3–34)

0.017

Progesterone (ng/mL) – M/P

0.2 ± 0.1 (0.1–0.4)

0.5 ± 0.4 (0.1–1.3)

0.149

Progesterone (ng/mL) – LF/A

0.2 ± 0.1 (0.1–0.3)

1.1 ± 2.2 (0.1-7.0)

0.262

  1. Data are presented as mean ± SD (Range); independent samples t test. Bold values indicate statistically significant differences between groups. *Significant difference from Menses within group. BMI = Body Mass Index, MAP = Mean Arterial Pressure, CRP = C-Reactive Protein, TC = Total Cholesterol, HDL = High-Density Lipoprotein, LDL = Low-Density Lipoprotein, TRIG = Triglycerides, HbA1c = Hemoglobin A1c, FBG = Fasting Blood Glucose, LH = Luteinizing Hormone