Fig. 3

(A) Circulating concentrations of estradiol across the menstrual cycle in women with type 1 diabetes using HBC ((HBC (+)) (closed triangle) and women with type 1 diabetes not using HBC ((HBC (-)) (open circle). * indicates significance from HBC (+) at each phase. † indicates significance from HBC (-) at menses. Repeated measures ANOVA; n = 18 (HBC (+) = 9, HBC (-) = 9). Vascular endothelial function across the menstrual cycle in women with type 1 diabetes using HBC ((HBC (+)) and women with type 1 diabetes not using HBC ((HBC (-)) using (B) Flow-mediated dilation; n = 18 (HBC (+) = 9, HBC (-) = 9) and (C) Nitroglycerin dilation; n = 9 (HBC (+) = 6, HBC (-) = 3). ǂ indicates a significant group main effect. # indicates a significant menstrual cycle phase main effect. Repeated measures ANOVA