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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice

Fig. 4

Prolonged Dasatinib treatment reduces cell senescence in the heart of db/db mice. Representative images (A) and bar chart (B) showing the levels of the senescent marker p16 in the heart, expressed as the percent of positive cells per total nuclei (stained blue by DAPI). Representative images (C) and bar chart (D) showing the level of the senescent marker p16 in the bone marrow. Bar graphs show individual values and means ± SEM. n = 7 to 8 animals per group

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Cardiovascular Diabetology

ISSN: 1475-2840