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Table 3 Covariate regression model for the probability of becoming metabolically impaired within 5 years*

From: Transitioning from having no metabolic abnormality nor obesity to metabolic impairment in a cohort of apparently healthy adults

Variable

p-value

OR

CI

Gender (males)

0.018

0.639

0.441–0.927

Age (first visit) years

< 0.001

1.031

1.017–1.045

Deltas of non-metabolic biomarkers

 Delta RBC

0.007

1.928

1.196–3.108

 Delta bilirubin

< 0.001

0.498

0.333–0.744

 Delta LDH

0.028

1.003

1.000–1.005

 Delta uric acid

0.025

1.191

1.022–1.387

Metabolic values from the 1st visit

 Diastolic

0.458

1.010

0.984–1.036

 Systolic

0.403

1.007

0.990–1.025

 Waist circumference

0.012

1.029

1.006–1.051

 BMI

0.003

1.099

1.033–1.169

 FPG

0.002

1.027

1.010–1.045

 Triglycerides

0.023

1.005

1.001–1.009

 HDL-C

0.003

0.985

0.975–0.995

 LDL-C

0.678

0.999

0.995–1.003

 Log (Hs-CRP)

0.011

1.390

1.080–1.790

  1. *All predictor variables were standardized before fitting the regression model. The model includes all coefficients listed in this table (bold values are significant) and the following non-significant coefficients: currently/previously smoking, delta WBC, delta BUN, delta potassium, delta ALT, delta creatinine. The sample comprised 1505 participants, with 817 individuals transitioning to metabolic impairment over time