Table 2 Comparison between the consistent metabolically healthy group and the group that developed at least 2 metabolic abnormalities according to data from the 1st visit
Healthy on both visits | Healthy on 1st visit, ≥ 2 metabolic components on 2nd visits | p-value | |
|---|---|---|---|
N | 1311 | 200 | |
Metabolic syndrome N (%) | 0 (0.0) | 39 (19.5) | |
Age, mean (SD) | 39.3 (9.7) | 43.1 (9.8) | < 0.001 |
Gender (males) N (%) | 740 (56.4) | 135 (67.5) | 0.003 |
Diastolic, mmHg | 71.4 (5.8) | 72.7 (5.9) | 0.006 |
Systolic, mmHg | 111.4 (8.9) | 113.8 (9.1) | < 0.001 |
BMI, kg/\({m}^{2}\) | 23.5 [21.7–25.2] | 25.9 [24.2–27.7] | < 0.001 |
Waist circumference, cm | 82.0 [75.0–89.0] | 88.0 [82.0–95.0] | < 0.001 |
FPG, mg/dL | 86.0 [81.0–90.0] | 88.0 [83.0–92.0] | 0.001 |
HbA1C (%) | 5.1 [4.9–5.3] | 5.2 [4.9–5.4] | 0.176 |
Triglycerides mg/dL | 74.0 [57.0–97.3] | 93.0 [69.5–121.5] | < 0.001 |
HDL mg/dL | 61.6 (13.9) | 56.1 (13.0) | < 0.001 |
Hs-CRP, mg/L | 0.9 [0.5–1.8] | 1.3 [0.8–2.5] | 0.032 |
High Hs-CRP > 3.0 md/dL, N (%) | 186 (14.4) | 34 (20.0) | 0.056 |
Creatinine mg/dL | 1.0 (0.1) | 1.1 (0.1) | 0.010 |
Neutrophils, % | 58.3 (7.8) | 58.9 (7.3) | 0.337 |
Lymphocytes, % | 31.0 (6.8) | 30.5 (6.8) | 0.370 |
Monocytes, % | 7.4 [6.3–8.7] | 7.5 [6.3–8.6] | 0.940 |
Eosinophils, % | 2.2 [1.4–3.3] | 2.2 [1.3–3.5] | 0.426 |
Basophils, % | 0.5 [0.4–0.6] | 0.5 [0.4–0.6] | 0.956 |
fibrinogen, g/L | 277.2 (56.5) | 293.5 (64.4) | < 0.001 |
Albumin, g/L | 45.1 (2.5) | 44.8 (2.4) | 0.194 |
BUN, mg/dL | 13.0 [11.0–16.0] | 14.0 [11.5–16.0] | 0.713 |
PLT, \({x10}^{3}\)/µL | 242.1 (54.7) | 240.7 (52.9) | 0.742 |
RBC, \(x{10}^{6}\)/µL | 4.7 (0.5) | 4.8 (0.4) | 0.045 |
WBC, \({x10}^{3}\)/µL | 6.2 [5.3–7.1] | 6.5 [5.6–7.6] | < 0.001 |
Hemoglobin, g/dL | 14.1 (1.3) | 14.3 (1.3) | 0.016 |
Bilirubin, mg/dL | 0.7 [0.6–1.0] | 0.7 [0.6–0.9] | 0.263 |
AST U/L | 21.0 [18.0–25.0] | 22.0 [19.0–25.0] | 0.359 |
ALT U/L | 19.0 [15.0–25.0] | 22.0 [17.0–29.0] | 0.008 |
Uric acid mg/dL | 5.0 (1.2) | 5.4 (1.3) | < 0.001 |
Globulin, g/L | 28.2 (3.2) | 28.5 (3.0) | 0.240 |
ALP U/L | 52.0 [43.0–64.0] | 55.0 [46.0–66.0] | 0.033 |
LDH U/L | 294.0 [264.0–326.0] | 301.0 [272.5–330.5] | 0.131 |
GGT U/L | 11.0 [7.0–16.0] | 14.0 [10.0–19.0] | 0.029 |
Phosphorus, mg/dL | 3.4 (0.5) | 3.4 (0.4) | 0.082 |
Protein total, g/L | 73.3 (4.0) | 73.3 (3.7) | 0.908 |
Total cholesterol mg/dL | 186.5 (32.5) | 194.1 (32.7) | 0.005 |
LDL mg/dL | 109.4 (28.7) | 119.0 (29.6) | < 0.001 |
Chloride, mmol/L | 104.0 (2.3) | 104.0 (2.1) | 0.967 |
Potassium, mmol/L | 4.3 (0.4) | 4.3 (0.3) | 0.693 |
Calcium, mg/dL | 9.2 (0.4) | 9.2 (0.4) | 0.532 |
Sodium, mmol/L | 141.1 (2.5) | 141.2 (2.8) | 0.524 |