Skip to main content

Table 1 Biochemical and anthropometric characteristics of patients with type 2 diabetes mellitus

From: Circulating PCSK9 as a prognostic biomarker of cardiovascular events in individuals with type 2 diabetes: evidence from a 16.8-year follow-up study

Variables

T2DM

N = 529

Age (years)

67 (62–72)

Sex (Males, %)

280 (53%)

Current smoking (n, %)

78 (15%)

BMI (Kg/m2)

28.1 (25.8–31.4)

Weight (Kg)

77 (69–86)

Waist-hip ratio

0.94 (0.89–0.98)

Total cholesterol (mg/dL)

204 (181–233)

LDL-C (mg/dL)

114 (96–136)

HDL-C (mg/dL)

50 (42–60)

non-HDL-C (mg/dl)

152 (130–177)

Triglycerides (mg/dL)

115 (83–159)

Remnant cholesterol (mg/dL)

34 (23–50)

ApoB (mg/dL)

100 (84–118)

ApoA1 (mg/dL)

164 (146–186)

PCSK9 (ng/mL)

260 (211–305)

Fasting glucose (mg/dL)

153 (133–183)

HbA1C (%)

7.3 (6.6–8.0)

Insulin (µUI/mL)

5.69 (3.66–8.62)

HOMA index

2.14 (1.39–3.56)

Hemoglobin (g/dL)

14.2 (13.4–15.2)

WBC (n/mm3)

6.57 (5.50–7.54)

Platelets (n/mm3)

209 (179–252)

hs-CRP (mg/L)

2.51 (1.23–4.65)

Fibrinogen (mg/dL)

298 (255–344)

Iron (µg/dL)

81 (64–96)

Ferritin (ng/mL)

88 (46–160)

Creatinine (mg/dL)

0.90 (0.70–1.00)

eGFR (mL/min)

81 (66–86)

Azotemia (mg/dL)

38 (32–46)

Uric acid (mg/dL)

4.6 (4.1–5.4)

Alanine aminotransferase (U/L)

39 (33–47)

Aspartate aminotransferase (U/L)

20 (16–24)

Total bilirubin (mg/dL)

0.6 (0.5–0.8)

Gamma-glutamyl transferase (U/L)

49 (39–61)

Disease duration (years)

14 (7–23)

Relevant medications (n, %)

 Any T2DM medication

403 (76%)

 Metformin

196 (37%)

 Sulphonylureas

257 (49%)

 Glinides

12 (2%)

 Insulin

95 (18%)

 Statins

103 (19%)

 Vitamin K antagonists

52 (10%)

T2DM complications (n, %)

 Retinopathy

149 (28%)

 Nephropathy

68 (13%)

 Neuropathy

98 (19%)

 History of MACE

79 (15%)

 Peripheral artery disease

50 (9%)

  1. Data are presented as median (interquartile range) or number (%) for continuous and categorical variables, respectively
  2. Apo apolipoprotein, BMI body mass index, eGFR estimated glomerular filtration rate, HbA1C hemoglobin A1C, HDL-C high-density lipoprotein cholesterol, HOMA Homeostasis model assessment for Insulin Resistance, hs-CRP high-sensitivity C-reactive protein, MACE major adverse cardiovascular events, LDL-C low-density lipoprotein cholesterol, PCSK9 proprotein convertase subtilisin/kexin type 9, WBC white blood cells, T2DM type 2 diabetes mellitus