The atherogenic index of plasma and carotid atherosclerosis in a community population: a population-based cohort study in China

Table 4 Performance of models with AIP to discriminate CA, CIMT, and plaques

Model	C statistic estimate (95% CI)	P-value	IDI	P-value	NRI	P-value
CA
Basic model A	0.705 (0.701, 0.709)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model A + AIP	0.707 (0.703, 0.711)	< 0.001	0.003	< 0.001	0.089	< 0.001
Basic model B	0.707 (0.703, 0.710)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model B + AIP	0.708 (0.704, 0.712)	< 0.001	0.003	< 0.001	0.082	< 0.001
Basic model C	0.720 (0.716, 0.725)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model C + AIP	0.721 (0.717, 0.726)	0.036	0.001	< 0.001	0.043	< 0.001
CMT
Basic model A	0.665 (0.661, 0.669)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model A + AIP	0.668 (0.664, 0.672)	< 0.001	0.003	< 0.001	0.088	< 0.001
Basic model B	0.667 (0.663, 0.671)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model B + AIP	0.669 (0.665, 0.673)	< 0.001	0.003	< 0.001	0.083	< 0.001
Basic model C	0.683 (0.679, 0.686)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model C + AIP	0.684 (0.680, 0.687)	0.004	0.001	< 0.001	0.046	< 0.001
Plaques
Basic model A	0.714 (0.711, 0.718)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model A + AIP	0.715 (0.712, 0.719)	< 0.001	0.001	< 0.001	0.060	< 0.001
Basic model B	0.716 (0.713, 0.720)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model B + AIP	0.717 (0.713, 0.721)	0.003	0.001	< 0.001	0.054	< 0.001
Basic model C	0.728 (0.725, 0.733)	Ref.	Ref.	Ref.	Ref.	Ref.
Basic model C + AIP	0.729 (0.726, 0.734)	0.112	0.0002	0.035	0.032	< 0.001

Abbreviations: CA, carotid atherosclerosis; CIMT, carotid intima–media thicking; AIP, Atherogenic Index of Plasma; NRI, net reclassification index; IDI, integrated discrimination index
Basic Model A: age, sex;
Basic Model B: age, sex, education, smoking, drinking, physical activity;
Basic Model C: sex, age, education, smoking, drinking, physical activity, BMI, SBP, DBP, TC, LDL-C, history of diseases including cerebrovascular disease, hypertension, and diabetes

ISSN: 1475-2840