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Table 1 Separation of T2D patients participating in CVOTs according to the presence (secondary prevention) or absence (primary prevention) of established CVD

From: Sodium–glucose transporter-2 inhibitors for prevention and treatment of cardiorenal complications of type 2 diabetes

Trial

Drug

Primary prevention

Secondary prevention

EMPA-REG

Empagliflozin

56 (0.8%)

6964 (99.2%)

CANVAS

Canagliflozin

2819 (27.8%)

7323 (72.2%)

DECLARE

Dapagliflozin

10 193 (59.4%)

6967 (40.6%)

VERTIS-CV

Ertugliflozin

82 (1%)

8155 (99%)

SCORED

Sotagliflozin

5440 (51.4%)

5144 (48.6%)

Total

 

18 590 (35.0%)

34 553 (65.0%)