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Table 4 Univariable Cox-regression analysis for plaque-morphological parameters as predictors of mortality following coronary intervention

From: Prognostic irrelevance of plaque vulnerability following plaque sealing in high-risk patients with type 2 diabetes: an optical coherence tomography study

 

HR (95% CI)

p

Stenosis characteristics

 Percent area stenosis (per 10%)

0.89 (0.54–1.48)

0.665

 MLA (per mm2)

0.88 (0.45–1.73)

0.711

 MLD (per mm)

0.31 (0.04–2.41)

0.264

 Stenosis lumen eccentricity (per 10%)

1.61 (1.14–2.28)

0.007

Lesion morphology

 Lesion length (per 10 mm)

1.69 (1.07–2.68)

0.026

 Lipid plaque (presence)

0.78 (0.34–1.80)

0.559

 Calcific plaque (presence)

4.06 (1.20–13.72)

0.024

 Fibrous plaque (presence)

1.29 (0.30–5.52)

0.733

 Presence of TCFA (presence)

0.87 (0.32–2.34)

0.871

 Minimal FCT (per 10 µm)

0.98 (0.78–1.23)

0.877

 Mean FCT (per 10 µm)

1.10 (0.91–1.33)

0.336

 Lipid arc (per 10°)

0.95 (0.83–1.08)

0.435

 Lipid volume index (per 100°*mm)

0.95 (0.84–1.09)

0.481

 Presence of microchannels (presence)

0.99 (0.43–2.28)

0.974

Calcification morphology

 Presence of microcalcifications (presence)

0.71 (0.24–2.10)

0.539

 Number of microcalcifications (per calcification)

0.93 (0.51–1.69)

0.932

 Presence of spotty calcifications (presence)

0.52 (0.22–1.28)

0.155

 Number of spotty calcifications (per calcification)

0.90 (0.71–1.14)

0.386

 Presence of macrocalcifications (presence)

8.23 (1.11–61.11)

0.039

 Number of macrocalcifications (per calcification)

1.43 (1.14–1.79)

0.002

 Total number of calcifications (per calcification)

1.06 (0.92–1.22)

0.433

 Mean calcium arc (per 10°)

1.10 (1.03–1.19)

0.005

 Calcium length (per mm)

1.06 (1.02–1.11)

0.008

 Calcium volume index (per 1000°*mm)

1.62 (1.21–2.17)

0.001

Plaque inflammation

 Presence of macrophages (presence)

1.22 (0.54–2.77)

0.632

 Macrophage arc (per 10°)

0.95 (0.78–1.15)

0.605

 Macrophage length (per mm)

0.84 (0.38–1.24)

0.385

 Macrophage volume index (per 100°*mm)

0.59 (0.24–1.42)

0.233

  1. MLA minimal luminal area, MLD minimal luminal diameter, TCFA thin capped fibroatheroma, FCT fibrous cap thickness