Fig. 5
From: SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats
Up-regulation of SIRT1 attenuated oxidative stress in diabetic MI/R rats. a Cardiac superoxide generation. b Top representative blot images. Bottom quantitative analysis of gp91phox expression. c MDA, malondialdehyde contents. d SOD superoxide dismutase activity. NS, non-diabetic sham rats; NIR, non-diabetic I/R rats receiving Ad-GFP; DS, diabetic sham rats; DIR, diabetic I/R rats receiving Ad-GFP; Ad.SIRT1, diabetic I/R rats receiving Ad-SIRT1. Values are mean ± SEM. n = 4–6. **P < 0.01 vs. NS; # P < 0.05, ## P < 0.01 vs. NIR; τ P < 0.05, ττ P < 0.01 vs. DIR