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Table 1 Echocardiography parameters for the four mouse groups

From: Successful metabolic adaptations leading to the prevention of high fat diet-induced murine cardiac remodeling

 

B6 CD

B6 HFD

MRL CD

MRL HFD

Morphological

 LVAWd (mm)

0.70 ± 0.08

0.81 ± 0.08*

1.07 ± 0.11

0.95 ± 0.15*

 LVAWs (mm)

0.97 ± 0.16

1.14 ± 0.13*

1.58 ± 0.22

1.38 ± 0.20*

 LVIDd (mm)

3.87 ± 0.29

3.91 ± 0.28

4.12 ± 0.25

4.17 ± 0.34

Diastolic

 E DT (ms)

20.04 ± 3.69

19.63 ± 4.15

13.59 ± 5.02

19.04 ± 5.77

 E/A

1.55 ± 0.32

1.81 ± 0.72

2.00 ± 0.55

2.13 ± 0.52

 E′/A′

1.05 ± 0.31

1.18 ± 0.61

1.33 ± 0.27

1.03 ± 0.16*

 EDV (μL)

65.86 ± 12.29

67.84 ± 11.24

75.54 ± 10.05

78.26 ± 13.37

Systolic

 EF %

56.33 ± 4.25

56.67 ± 8.84

70.25 ± 8.97

64.63 ± 11.30

 FS %

29.03 ± 2.69

29.58 ± 6.67

39.91 ± 7.59

35.74 ± 8.94

 HR

439.00 ± 40.69

448.77 ± 54.40

441.90 ± 54.45

441.08 ± 35.52

  1. Italics indicate significance (p < 0.05) versus the control diet group of the same strain
  2. N > 14
  3. LVAWd left ventricular anterior wall in diastole, LVAWs in systole, LVIDd interior diameter in diastole, E DT E wave deceleration time, EDV left ventricular end diastolic volume